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276872-89-0

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276872-89-0 Usage

Uses

1-Boc-3-methylenepiperidine is a reagent used in the preparation of analogs of spirocyclic quinuclidinyl-Δ2-isoxazolines as potent and selective α7 nicotinic agonists.

Check Digit Verification of cas no

The CAS Registry Mumber 276872-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,6,8,7 and 2 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 276872-89:
(8*2)+(7*7)+(6*6)+(5*8)+(4*7)+(3*2)+(2*8)+(1*9)=200
200 % 10 = 0
So 276872-89-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO2/c1-9-6-5-7-12(8-9)10(13)14-11(2,3)4/h1,5-8H2,2-4H3

276872-89-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Methylene-1-piperidinecarboxylic acid tert-butyl ester

1.2 Other means of identification

Product number -
Other names N-Boc-3-Methylenepiperidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:276872-89-0 SDS

276872-89-0Relevant articles and documents

Intramolecular radical rearrangement reactions of 2-methyleneaziridines: Application to the synthesis of substituted piperidines, decahydroquinolines, and octahydroindolizines

Prevost, Natacha,Shipman, Michael

, p. 2383 - 2385 (2001)

(matrix presented) Intramolecular 5-exo cyclization of 3-(2-methyleneaziridin-1-yl)propyl radicals leads to the generation of a highly strained, bicyclic aziridinylcarbinyl radical that undergoes C-N bond fission to the ring-expanded aminyl radical. This

AMIDE DERIVATIVES COMPRISING HETEROCYCLOALKYL RING

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Paragraph 0239-0241, (2020/05/20)

PROBLEM TO BE SOLVED: To provide compounds or pharmacologically acceptable salts thereof that have excellent EP300 and/or CREBBP histone acetyltransferase inhibitory activity. SOLUTION: The invention provides compounds represented by the formula (1) in the figure or pharmacologically acceptable salts thereof. (In the formula (1), ring Q1, ring Q2, ring Q3, X and L are as defined in the specification.) SELECTED DRAWING: None COPYRIGHT: (C)2020,JPO&INPIT

SPIROCYCLIC MOLECULES AS PROTEIN KINASE INHIBITORS

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Paragraph 00253-00255, (2013/03/26)

The present invention relates to spirocyclic compounds of formula I, namely spirocyclic (1H-pyrazol-4-yl)-3-(1-(2,6-dichloro-3-fiuorophenyl) ethoxy)pyridin-2-amines having protein kinase inhibitory activity, and methods of synthesizing and using such compounds. Preferred compounds are c-Met and/or ALK inhibitors useful for the treatment of abnormal cell growth, such as cancers

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