357400-02-3Relevant articles and documents
Reaction of Lys-Tyr-Lys triad mimics with benzylpenicillin: Insight into the role of Tyr150 in Class C β-lactamase
Kato-Toma, Yoko,Ishiguro, Masaji
, p. 1161 - 1164 (2001)
Small and simple molecules mimicking a Lys-Tyr-Lys triad and some "mutant" derivatives were designed and synthesized. These compounds react with benzylpenicillin in water (75 mM phosphate buffer, pH 7), apparently through general base assistance by the ph