357439-44-2Relevant academic research and scientific papers
Stereocontrolled synthesis of the ABCDE ring moiety of ciguatoxin CTX3C
Kobayashi, Shoji,Takahashi, Yusuke,Komano, Kazuo,Alizadeh, Babak H.,Kawada, Yuuya,Oishi, Tohru,Tanaka, Shin-Ichiro,Ogasawara, Yoshihiro,Sasaki, Shin-Ya,Hirama, Masahiro
, p. 8375 - 8396 (2007/10/03)
The ABCDE ring moiety of ciguatoxin CTX3C, a major causative agent of ciguatera poisoning, was stereoselectively synthesized. The key transformations are a chiral auxiliary-based asymmetric alkylation and an asymmetric aldol condensation, which controlled
Highly stereocontrolled synthesis of the ABCD ring fragment of ciguatoxin CTX3C
Oishi,Tanaka,Ogasawara,Maeda,Oguri,Hirama
, p. 952 - 954 (2007/10/03)
A combination of asymmetric alkylation using (1R,2S)-1-amino-2-indanol derivative as a chiral auxiliary and the ring-closing metathesis reaction was shown to be an efficient method for synthesizing the ABCD ring fragment of ciguatoxin CTX3C.
