35756-30-0

Upstream product

• 31844-92-5 2-chloro-N-phenyl-3-oxobutanamide 
• 540-63-6 ethane-1,2-dithiol 
• 35756-29-7 5,6-dihydro-3-methyl-1,4-dithiin-2-carboxylic acid 
• 135081-30-0 trans-2-methyl-N-phenyl-1,3-dithiolane-2-acetamide 1-oxide 
• 119878-86-3 3-bromo-2-oxo-N-phenylbutanamide 
• 85997-36-0 2-Methyl-N-phenyl-1,3-dithiolane-2-acetamide 
• 135081-30-0 cis-2-methyl-N-phenyl-1,3-dithiolane-2-acetamide 1-oxide 
• 138481-40-0 3-hydroxy-2-methyl-N-phenyl-1,4-dithian-3-carboxamide 
• 102-01-2 N-phenylacetoacetamide 

Downstream Products

• 1003593-82-5 N,3-dimethyl-N-phenyl-5,6-dihydro-1,4-dithiine-2-carboxamide 

Relevant academic research and scientific papers

Rearrangement mechanisms of 1,3-dithiolane sulfoxides

Oxidation of sulfide 4 gave a mixture of cis and trans monosulfoxides 5 and 6 is as major and minor products, respectively, plus a small amount of disulfoxides 7. The structural assignments of cis and trans sulfoxides 5 and 6 were based on 1H N

REARRANGEMENT MECHANISMS OF SOME CYCLIC SULFOXIDES.

Under neutral conditions cis sulfoxides 5 underwent a sigmatropic rearrangement with 2-methylene hydrogens to give sulfenic acids 18, followed by cyclization to dihydro-1,4-dithiins 2.The trans sulfoxides 6 rearranged involving 2-methyl hydrogens to form

1,4-Dithiinoxides

1,4-Dithiinoxides which may be substituted with various radicals, compositions containing said products and methods useful in the treatment of ulcers are disclosed. The products are prepared by oxidation of the correspondingly substituted dithiin.