357604-43-4Relevant academic research and scientific papers
Enantioselective Addition of Alkynyl Esters and Ethers to Aldehydes Catalyzed by a Cyclopropyl Amino Alcohol Based Zinc Catalyst
Bian, Qinghua,Li, Fengqi,Li, Shuoning,Ma, Sijie,Walsh, Patrick J.,Wang, Lifeng,Wang, Min,Zhong, Jiangchun,Zhou, Yun
supporting information, p. 60 - 64 (2019/12/30)
A novel and highly enantioselective synthesis of hydroxyalkynyl esters and ethers through the asymmetric addition of alkynyl esters or ethers to aldehydes promoted by a cyclopropyl amino alcohol based zinc catalyst has been developed. The method afforded a library of new enantioenriched hydroxyalkynol esters and ethers (up to 93percent yield; 95percent ee), and it was compatible with a broad range of functional groups. Moreover, it could be used in the synthesis of carbon-chain-elongated enantioenriched hydroxyalkynol esters and (2 R,5 R)-musclide-A1, a cardiotonic potentiating principle from musk.
Combining oxidative N-heterocyclic carbene catalysis with click chemistry: A facile one-pot approach to 1,2,3-triazole derivatives
Ramanjaneyulu,Reddy, Virsinha,Arde, Panjab,Mahesh, Sriram,Anand, R. Vijaya
, p. 1489 - 1496 (2013/07/26)
A combination of the oxidative N-heterocyclic carbene catalysis and click chemistry has been explored for the direct, one-pot synthesis of 1,2,3-triazole derivatives from aromatic aldehydes. This procedure was found to be very efficient and a variety of 1
WATER SOLUBLE ESTERS OF [N-(4-AMINO-2-BUTYNYL)] WITH ANTICANCER ACTIVITY
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Page/Page column 51; 52, (2008/06/13)
The present invention relates to water soluble esters of [N-(4-amino-2-butynyl)] or 4-(N-substituted amino)-2-butynyl-1-esters and methods for production of said esters and the use of the esters for treatment of cancer.
