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• 201852-49-5 potassium (E)-trifluoro(styryl)borate 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 100-42-5 styrene 
• 71418-88-7 5-(phenylethynyl)pyrimidine 
• 53967-68-3 5-vinyl-pyrimidine 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

Functionalization of the Imidazole Backbone by Means of a Tailored and Optimized Oxidative Heck Cross-Coupling

A general and selective Pd-catalyzed cross-coupling of aromatic boronic acids with vinyl-imidazoles is disclosed. Unlike most cross-coupling reactions, this method operates well in absence of bases avoiding the formation of by-products. The reactivity is highly enhanced by the presence of nitrogen-based ligands, in particular bathocuproine. The method involves MnO2 as oxidant for the oxidation Pd (0)→Pd (II), a much weaker oxidant than previously reported in the literature. This allows for the use of reactants that possess a multitude of functional groups. A scope and limitation study involving a series of 24 boronic acids, whereof 18 afforded TMs in yields in the range 41–95%. The disclosed method constitutes the first general method for the oxidative Heck cross-coupling on the imidazole scaffold, which moreover operates with a selection of other heterocycles. (Figure presented.).

Methanol as the Hydrogen Source in the Selective Transfer Hydrogenation of Alkynes Enabled by a Manganese Pincer Complex

The first base metal-catalyzed transfer hydrogenation of alkynes with methanol is described. An air and moisture stable manganese pincer complex catalyzes the reduction of a variety of different alkynes to the corresponding (Z)-olefins in high yields. The

The aminocyclodextrin/Pd(OAc)2 complex as an efficient catalyst for the Mizoroki-Heck cross-coupling reaction

An aminocyclodextrin/Pd(OAc)2 complex is used as an efficient, reusable catalyst in the Mizoroki-Heck reaction of aryl halides/triflates with olefins to give carbon-carbon-coupled products in good to excellent yields. This simple, efficient catalytic system is applicable to a wide range of aryl and heteroaryl halides/triflates and olefins. This environmentally benign procedure is less hazardous, milder, uses a catalytic amount of ligand and Pd(OAc) 2, avoids an inert atmosphere, and catalyst recovery and reusability are achieved. Copyright

Transforming Suzuki-Miyaura cross-couplings of MIDA boronates into a green technology: No organic solvents

New technology has been developed that enables Suzuki-Miyaura couplings involving widely utilized MIDA boronates to be run in water as the only medium, mainly at room temperature. The protocol is such that no organic solvent is involved at any stage; from the reaction through to product isolation. Hence, using the E factor scale as a measure of greenness, the values for these cross-couplings approach zero.

1,3,2,4-Diazadiphosphetidines as new P-N ligands for palladium-catalyzed Heck reaction in water

1,3,2,4-Diazadiphosphetidine-based phosphazane class have been used as a new generation of heterogeneous bidentate P(III) ligands containing nitrogen for base-free Pd(II) catalyzed C-C bond formation through Heck coupling reaction of aryl iodides, bromides and chlorides in water with styrene, n-butyl acrylate, 1-octene, and cyclohexene. The reactions occur heterogeneously in water and homogenously or partially heterogeneously in appropriate organic solvents. The ligand together with its Pd(0) complex is easily separated by filtration and reused for several runs.

2-Aminophenyl diphenylphosphinite as a new ligand for heterogeneous palladium-catalyzed Heck-Mizoroki reactions in water in the absence of any organic co-solvent

In this article, 2-aminophenyl diphenylphosphinite has been introduced as a new ligand for the Heck-Mizoroki reactions of aryl halides with styrene and n-butylacrylate in water in the presence of palladium acetate. This ligand is easily prepared from the reaction of chlorodiphenyl phosphine with 2-aminophenol in high yield. Pre-catalyst [Pd(OAc)2] in the presence of the ligand produces a black solid mass. The solid catalyst has been recycled for the reaction of bromobenzene with styrene for six runs without appreciable loss of its catalytic activity.

Suzuki-Miyaura cross-coupling reactions of potassium alkenyltrifluoroborates

We have previously reported that the palladium-catalyzed cross-coupling reaction of air-stable potassium alkenyltrifluoroborates with aryl halides and triflates proceeds readily with good yields. Recent progress in outlining the scope and limitations of s