357913-53-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Production:
3-(Methylsulfonyl)propyl Methanesulfonate is used as a reagent and intermediate in the synthesis of pharmaceuticals and agrochemicals, leveraging its strong nucleophilic properties to facilitate chemical reactions and the formation of desired products.
Used in Polymer Manufacturing:
In the polymer industry, 3-(Methylsulfonyl)propyl Methanesulfonate is utilized as a solvent and stabilizer, contributing to the processability and stability of polymer materials during manufacturing.
Used in Organic Synthesis:
3-(Methylsulfonyl)propyl Methanesulfonate is employed as a reagent in various organic synthesis processes, where its nucleophilic nature aids in the formation of new chemical bonds and the synthesis of complex organic molecules.

Upstream product

• 2058-49-3 3-(methylsulfonyl)propan-1-ol 
• 124-63-0 methanesulfonyl chloride 
• 232944-38-6 3-(methylthio)propyl methanesulfonate 

Downstream Products

• 1613302-17-2 5-bromo-1,3-difluoro-2-(3-methanesulfonylpropoxy)benzene 
• 1246405-50-4 1-({4-(4-Chlorophenyl)-5-(2,4-dichlorophenyl)-3-[3-(methylsulfonyl)propoxy]thien-2-yl}carbonyl)-4-phenylpiperidine-4-carboxamide 
• 1309686-40-5 2-methoxy-4-(3-(methylsulfonyl)propoxy)-1-nitrobenzene 

Relevant academic research and scientific papers

SUBSTITUTED GUANIDINE DERIVATIVE

The present invention provides a compound of general formula (I) (wherein, R1, X, p and q are as described in the present description and claims), or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing that compound.

Novel benzoxazolone compound

PROBLEM TO BE SOLVED: To provide a therapeutic agent for diseases such as neuropathic pain, nociceptive pain, inflammatory pain, small diameter fiber neuropathy, erythromelalgia, paroxysmal extreme pain disorder, dysuria or multiple sclerosis. SOLUTION: There is provided a benzoxazolone compound represented by the formula (1) or a pharmaceutically acceptable salt. (1), where R1 and R2 are each independently H or C1-6 alkyl, where the alkyl may be substituted by hydroxy, C1-4 alkylsulfonyl, aminocarbonyl or 4 to 7-membered heterocycloalkyl, or the like, L is C1-6 alkylene, R3 is C1-6 alkyl, C3-7 cycloalkyl, where the cycloalkyl may be substituted by halogen or hydroxy or the like, C6-10 aryl, where the aryl may be substituted by halogen, C1-4 alkyl or C1-4 haloalkyl or the like, R4 is H, halogen or C1-4 alkyl. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula (I), wherein R1, R2, R3, R4, R5 and Ar are as described herein, compositions including compounds and methods of using the compounds.

SPIROINDOLINONE PYRROLIDINES

There are provided compounds of the formula wherein X, Y and R1 to R8 are described herein along with the enantiomers, pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.

Sulfur containing compounds

This invention is directed to novel and known stufur containing compounds and pharmaceutically acceptable salts thereof that have utility as antifungals and as antiproliferative agents against mammalian cells, in particular cancer cells and most particularly leukemia-derived cells. The invention provides a method for synthesizing certain of the sulfur containing compounds that is more efficient than previously known methods.

Structure-activity relationships for selected sulfur-rich antifungal compounds

A series of sulfur compounds has been prepared and tested against two kinds of fungi: Aspergillus niger and Aspergillus flavus. Results on various sulfone disulfides and ester disulfides have led to the formulation of a proposed mechanism for fungicidal behaviour that permits one to anticipate which structures will be antifungal.

σ Ligands with subnanomolar affinity and preference for the σ2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines

Spiro[isobenzofuran-1(3H),4'-piperidines] and the corresponding benzofuran and benzopyran derivatives have been synthesized and evaluated as σ ligands. The compounds are related to Lu 28-179 (1'[4-[1(4fluorophenyl)-1H-indol-3- yl]-1-butyl]spiro[isobenzofu