357916-54-2Relevant academic research and scientific papers
Photochemical synthesis of novel dideoxynucleosides
Lee-Ruff,Margau
, p. 185 - 196 (2001)
A series of 2′,3′-dideoxynucleosides based on the apiose family was prepared from photochemical ring-expansion of a common cyclobutanone precursor. The starting ketone, (±) 3-[2′-(benzoyloxy)ethyl]-2,2-dimethylcyclobutanone (12) was prepared from commercially available (±)α-pinene. Since the optically pure antipodes of α-pinene are also commercially available, these nucleosides can be prepared optically pure using the identical procedure.
