357928-51-9

Upstream product

• 32077-99-9 5'-deoxy-5'-acetamido-2',3'-O-isopropylidene adenosine 
• 21950-36-7 5'-amino-5'-deoxy-2',3'-O-isopropylideneadenosine 

Downstream Products

• 357928-53-1 3-{Acetyl-[(3aR,4R,6R,6aR)-6-(6-benzyloxycarbonylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl]-amino}-3-oxo-propionic acid methyl ester 
• 357928-40-6 3-{Acetyl-[(3aR,4R,6R,6aR)-6-(6-benzyloxycarbonylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl]-amino}-2-diazo-3-oxo-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of a new class of 5'-functionalized adenosines using a rh(ii)-catalyzed 1,3-dipolar cycloaddition.

[reaction: see text] Chemically protected adenosine was functionalized at the 5' position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5' position of adenosine.