357935-93-4Relevant academic research and scientific papers
Design and development of arrayable syntheses to accelerate SAR studies of pyridopyrimidinone and pyrimidopyrimidinone
Wan, Zehong,Yan, Hongxing,Hall, Ralph F.,Lin, Xichen,Livia, Stefano,Respondek, Tomasz,Widdowson, Katherine L.,Zhu, Chongjie,Callahan, James F.
scheme or table, p. 370 - 372 (2009/04/19)
Chemoselectivity of chlorine versus methylthio (-SCH3), methylsulfinyl (-SOCH3), or methylsulfonyl [-S(O)2CH3] in either functionalization or substitution of pyridopyrimidinone and pyrimidopyrimidinone was studi
NOVEL COMPOUNDS
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Page/Page column 78-79, (2008/06/13)
Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds, and 1,5,7-trisubstituted-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-(1H)-one compounds and compositions, and their use in therapy as CSBP/RK/p38 kinase inhibitors.
NOVEL COMPOUNDS
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Page/Page column 101-102, (2010/11/29)
Novel substituted 1,5,7-trisubstituted-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2-(1H)-one compounds and compositions, and their use in therapy as CSBP/RK/p38 kinase inhibitors.
PROCESS FOR PREPARING PYRIDO[2,3-D]PYRIMIDIN-7-ONE AND 3,4-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-2(1H)-ONE DERIVATIVES
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Page/Page column 81-82, (2008/06/13)
The present invention is directed to a novel method of preparing of 2,4,8- trisubstituted pyrido[2,3-d]pyrimidin-7-one pharmacophores of Formula (II) or (Ha) wherein GHs CH2 Or NH: G2 is CH or nitrogen; Rx is chloro, bromo, iodo, or O-S(O)
NOVEL COMPOUNDS
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Page/Page column 114, (2008/06/13)
Novel substituted l,5,7-trisubstituted-354-dihydro-pyriinido[4,5-(flpyrimidin- 2-(2H)-one compounds and compositions, and their use in therapy as CSBP/RK/p38 kinase inhibitors.
1,5- disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
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, (2008/06/13)
Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
