357979-48-7Relevant academic research and scientific papers
Synthesis of spiro- and fused heterocycles by palladium catalysed carbo- and heteroannulation cascades of allenes
Grigg,Koeppen,Rasparini,Sridharan
, p. 964 - 965 (2001)
Two novel palladium catalysed cascade processes involving the generation of a (π-allyl)palladium intermediate from allenes in an intra- or intermolecular fashion, followed by regioselective intramolecular nucleophilic addition of amines, alcohols or malon
A Modular Approach for the Palladium-Catalyzed Synthesis of Bis-heterocyclic Spirocycles
Marchese, Austin D.,Durant, Andrew G.,Lautens, Mark
supporting information, p. 95 - 99 (2022/01/04)
A simple and modular approach toward bis-heterocyclic spirocycles using palladium catalysis is reported. The enclosed methodology leverages a Mizoroki–Heck-type reaction to generate a neopentylpalladium species. This species can undergo intramolecular C–H
