35799-21-4

Upstream product

• 123-75-1 pyrrolidine 
• 100-28-7 4-Nitrophenyl isocyanate 

Downstream Products

• 1357381-90-8 pyrrolidine-1-carboxylic acid (4-acryloylaminophenyl)-amide 
• 851651-90-6 Pyrrolidine-1-carboxylic acid (4-amino-phenyl)-amide 

Relevant academic research and scientific papers

Synthesis of ureas in the bio-alternative solvent Cyrene

Cyrene as a bio-alternative solvent: a highly efficient, waste minimizing protocol for the synthesis of ureas from isocyanates and secondary amines in the bio-available solvent Cyrene is reported. This method eliminated the use of toxic solvents, such as

Thiazolidinones, their production and use as pharmaceutical agents

Thiazolidinones of general formula I in which Q, A, B, X, R1 and R2 have the meanings that are indicated in the description, as well as those of general formula IA in which Q, A, B, X, R1 and R2a have the meanings that are indicated in the description, their production and use as inhibitors of the polo-like kinase (PLK) for treating various diseases as well as intermediate products for the production of thiazolidinones are described.