35807-94-4Relevant academic research and scientific papers
Synthesis of novel glycosyl imidazolidine-2,4,5-trione derivatives
Liu, Wei Wei,Zhang, Qiang,Gong, Feng,Huo, Yun Feng,Tao, Chuan Zhou,Cao, Zhi Ling,Shi, Da Hua
, p. 161 - 165 (2015)
A series of glycosyl imidazolidine-2,4,5-trione derivatives were achieved by condensing per-O-acetylated glucosamine, triphosgene, amines and oxalyl chloride. The convenient and efficient method afforded the desired products with good to excellent yields
Synthesis and antifungal activity of d-glucopyranosyl ureas and d-glucofurano-imidazolidine-2-ones
Tang, Xuan,Xue, Feng,Ma, Hongju,Cao, Xiufang,Chen, Changshui,Li, Xuegang
, p. 805 - 820 (2013/06/05)
A series of N-β-d-glucopyranosyl-N'-substituted phenyl ureas were synthesized by reaction of glucosyl isocyanate with arylamines and glycosamine with aryl isocyanates, and a series of d-glucofurano-imidazolidine-2-ones were obtained via deacetylation of glycosylureas. Although some of the compounds have already been described, most were prepared for the first time in this work. The structures of all the compounds synthesized were confirmed by IR, 1H NMR, and, in part, by 13C NMR. Antifungal activity of the title compounds was determined against four kinds of plant pathogenic fungi, Sclerotinia sclerotiorum, Fusarium graminearum, Fusarium oxysporum, and Bipolaris maydis. Preliminary bioassay indicates that most of glycosylureas had some activity against S. sclerotiorum; for some, the antifungal activity was strong. However, most of the imidazolidine-2-ones had weak antifungal activity.
