3581-01-9

Basic information

• Product Name: 2-(butylthio)ethanamine
• Synonyms: 2-(butylthio)ethanamine;ETHANAMINE, 2-(BUTYLTHIO)-;UKRORGSYN-BB BBV-065295
• CAS NO: 3581-01-9
• Molecular Formula: C6H15NS
• Molecular Weight: 133.255
• Mol File: 3581-01-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 199.2 °C at 760 mmHg
• Flash Point: 74.3 °C
• Appearance: /
• Density: 0.917g/cm³
• Vapor Pressure: 0.345mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: 2-(butylthio)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(butylthio)ethanamine(3581-01-9)
• EPA Substance Registry System: 2-(butylthio)ethanamine(3581-01-9)

Safety Data

• Hazardous Substances Data: 3581-01-9(Hazardous Substances Data)

Usage

General Description

2-(butylthio)ethanamine is a chemical compound with the molecular formula C6H15NS. It is an organic compound that contains an amine functional group and a butylthio (sulfanylbutyl) group. The structure of this compound consists of an ethyl chain attached to a sulfur atom, which is part of the butylthio group. 2-(butylthio)ethanamine is commonly used in the synthesis of various pharmaceuticals and organic compounds due to its amine functional group, which can undergo various chemical reactions such as alkylation and acylation. It is also used as an intermediate in the production of pesticides, herbicides, and rubber chemicals. However, it is important to handle this compound with caution, as it can be harmful if ingested or inhaled, and may cause skin and eye irritation upon contact.

InChI:InChI=1/C6H15NS/c1-2-3-5-8-6-4-7/h2-7H2,1H3

Upstream product

• 109-65-9 1-bromo-butane 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 109-79-5 n-butanethiol 
• 2576-47-8 2-bromoethylamine hydrobromide 
• 151-56-4 ethyleneimine 
• 60-23-1 Cysteamine 

Downstream Products

• 66859-98-1 3-(2-butylsulfanyl-ethyl)-2-phenyl-thiazolidin-4-one 
• 66859-94-7 benzylidene-(2-butylsulfanyl-ethyl)-amine 
• 71416-97-2 Cyclohex-1-ene-1,2-dicarboxylic acid 1-[(2-butylsulfanyl-ethyl)-amide] 2-[(4-chloro-2-fluoro-phenyl)-amide] 

Relevant articles and documents

Thermoresponsive Sulfone and Sulfoxide-Containing Polyacrylamides

A series of thermoresponsive polyacrylamides containing sulfide, sulfone, or sulfoxide was successfully prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. The thermal properties of polyacrylamides with sulfone or sulfoxide, which have not been studied before, were investigated for the first time. While poly[N-(2-(propylsulfonyl)ethyl)acrylamide] (P2SO2) with sulfone groups was water insoluble, poly[N-(2-(propylsulfinyl)ethyl)acrylamide] (P2SO) with sulfoxide groups was water soluble, indicating that the sulfoxide moiety is more hydrophilic than sulfone. By controlling the end of the polymer chain, we synthesized poly[N-(2-(ethylsulfonyl)ethyl)acrylamide] (P1SO2) and poly[N-(2-(butylsulfinyl)ethyl)acrylamide] (P3SO), which exhibit an lower critical solution temperature (LCST) in water around 24–26°C. For adjusting a wide range of LCST, we synthesized the random copolymers by controlling the initial feed ratio of hydrophobic M2SO2 and hydrophilic M2SO. The amphiphilic block copolymers were also synthesized and assembled in water to yield the micelles. After adding H2O2 to this micellar solution, the hydrophobic block was oxidized and converted to a hydrophilic block, leading to the transformation of micelles to unimers.

ELECTROCHEMICAL SYNTHESIS OF FUNCTIONALLY SUBSTITUTED SULFIDES

A method of synthesis of functionally substituted sulfides by cathode electrolysis of thiols on platinum or carbon glass electrodes in the presence of organyl halides was developed.The method of the rotating disk electrode with ring showed that this process passes through the intermediate formation of a thiolate anion on the cathode, and its reaction with the organyl halide results in a high yield of sulfides.