35824-20-5

Upstream product

• 4546-72-9 N₆-benzoyl-2'-deoxyadenosine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 211919-84-5 N-[9-((2R,4S,5S)-4-Hydroxy-5-phenylsulfanylmethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 184229-73-0 N-(9-{(2R,4S,5S)-5-[Bis-(4-methoxy-phenyl)-phenyl-methylsulfanylmethyl]-4-hydroxy-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide 
• 82305-19-9 N-[9-(4-hydroxy-5-iodomethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 184229-74-1 Diisopropyl-phosphoramidous acid (2S,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methylsulfanylmethyl]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 
• 1403036-41-8 N-benzoyl-3'-triisopropylsilyl-5'-tosyl-2'-deoxyadenosine 
• 1403036-68-9 N-benzoyl-3'-triisopropylsilyl-8,5'(R)-cyclo-2'-deoxyadenosine 
• 1403036-60-1 N-benzoyl-3'-triisopropylsilyl-5'-mesyl-8,5'(S)-cyclo-2'-deoxyadenosine 
• 1403036-56-5 N-benzoyl-3'-triisopropylsilyl-8,5'(S)-cyclo-2'-deoxyadenosine 
• 1403036-53-2 N-benzoyl-3'-triisopropylsilyl-5'-keto-8,5'-cyclo-2'-deoxyadenosine 
• 1403036-49-6 N-benzoyl-3'-triisopropylsilyl-8,5'-cyclo-2',5'-dideoxyadenosine 
• 1403036-45-2 N-benzoyl-3'-triisopropylsilyl-5'-iodo-2'-deoxyadenosine 
• 1403036-89-4 N-benzoyl-5'-(1-ethoxyethyl)-8,5'(R)-cyclo-2'-deoxyadenosine 
• 1403036-84-9 N-benzoyl-5'-(1-ethoxyethyl)-8,5'(S)-cyclo-2'-deoxyadenosine 
• 1403036-79-2 N-benzoyl-3'-triisopropylsilyl-5'-(1-ethoxyethyl)-8,5'(R)-cyclo-2'-deoxyadenosine 

Relevant academic research and scientific papers

Synthesis and properties of DNA containing cyclonucleosides

Here, we present efficient syntheses of the R and S diastereomers of 8,5′-cyclo-2′-deoxyadenosine and 6,5′-cyclo-2′- deoxyuridine. We incorporated these interesting nucleosides into DNA to study how the cyclo linkage affects the stability of duplex formation.

Efficient solid phase synthesis of cleavable oligodeoxynucleotides based on a novel strategy for the synthesis of 5′-S-(4,4′-dimethoxytrityl)- 2′-deoxy-5′-thionucleoside phosphoramidites

The incorporation of a specific cleavage site into an oligodeoxynucleotide can be achieved by utilizing the four 5′-S-(4,4′-dimethoxytrityl)- 2′-deoxy-5′-thionucleoside 3′-(2-cyanoethyl diisopropylphosphoramidites) 5 and 15a-c (Fig.1). Based on the silver