358366-12-8Relevant articles and documents
A stereochemically flexible approach to pyrrolidines based on 5-endo-trig iodocyclisations of homoallylic sulfonamides
Jones,Knight,Hibbs
, p. 1182 - 1203 (2007/10/03)
5-endo-trig Iodocyclisations of the (E)-homoallylic sulfonamides 24 in the presence of potassium carbonate give excellent yields of trans-2,5-disubstituted-3-iodopyrrolidines 36. In the absence of base, these initial kinetic products undergo rapid isomeri