99878-46-3Relevant academic research and scientific papers
Overcoming Electron-Withdrawing and Product-Inhibition Effects by Organocatalytic Aerobic Oxidation of Alkylpyridines and Related Alkylheteroarenes to Ketones
Wang, Hua,Liu, Jie,Qu, Jian-Ping,Kang, Yan-Biao
, p. 3942 - 3948 (2020)
An organocatalyzed aerobic benzylic C-H oxidation of alkyl and aryl heterocycles has been developed. This transition metal-free method is able to overcome the electron-withdrawing effect as well as product-inhibition effects in heterobenzylic radical oxidation. A variety of ketones bearing N-heterocyclic groups could be prepared under relatively mild conditions with moderate to high yields.
5-HT1f agonist
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Page column 26, (2010/02/08)
The present invention relates to a compound of formula I and a process for making: or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1Freceptors and inhibiting neuronal protein extravasation in a mammal.
