358656-23-2Relevant academic research and scientific papers
Pyrazoline analogs as potential anticancer agents and their apoptosis, molecular docking, MD simulation, DNA binding and antioxidant studies
Rana, Manish,Arif, Rizwan,Khan, Faez Iqbal,Maurya, Vikas,Singh, Raja,Faizan, Md Imam,Yasmeen, Shama,Dar, Sajad Hussain,Alam, Raquib,Sahu, Ankita,Ahmad, Tanveer,Rahisuddin
, (2021)
N-formyl pyrazoline derivatives (3a–3l) were designed and synthesized via Michael addition reaction through cyclization of chalcones with hydrazine hydrate in presence of formic acid. The structural elucidation of N-formyl pyrazoline derivatives was carri
Design, synthesis and insecticidal activity of novel semicarbazones and thiosemicarbazones derived from chalcone
Cheng, Wei,Xiao, Tingting,Qian, Weifeng,Lu, Tong,Zhang, Tingting,Tang, Xiaorong
, p. 3801 - 3809 (2020/03/23)
Thirty semicarbazone and thiosemicarbazone derivatives (2a–w and 4a–g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure o
Pyrazoline derivatives as tubulin polymerization inhibitors with one hit for Vascular Endothelial Growth Factor Receptor 2 inhibition
Yang, Bing,Zhou, Jiahua,Wang, Fa,Hu, Xiao-Wei,Shi, Yujun
, (2021/07/13)
In this work, to check the effect of the transposition of the rings in typical patterns, a series of pyrazoline derivatives 3a-3t bearing the characteristic 3,4,5-trimethoxy phenyl and thiophene moieties were synthesized and evaluated as tubulin polymeriz
Thiophene chalcone semicarbazone Schiff base compounds, and preparation method and applications thereof
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Paragraph 0029; 0054; 0055, (2016/10/10)
The invention provides thiophene chalcone semicarbazone Schiff base compounds, and a preparation method and applications thereof. Structure general formula of the thiophene chalcone semicarbazone Schiff base compounds is represented by a formula I in the invention, wherein R is used for representing single substitution or double substitution, and is used for representing fluorine atoms, chlorine atoms, bromine atoms, iodine atoms, methyl, methoxyl, or phenyl. The thiophene chalcone semicarbazone Schiff base compounds are simple and novel in structure, are convenient to be synthesized, and possess excellent control effects on plant pathogenic fungi. The thiophene chalcone semicarbazone Schiff base compounds are taken as plant pathogenic fungi inhibitors for the first time.
