358721-54-7

Basic information

• Product Name: 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride
• Synonyms: 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride
• CAS NO: 358721-54-7
• Molecular Formula: C₈H₁₀ClNO₂
• Molecular Weight: 187.6235
• Mol File: 358721-54-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride(358721-54-7)
• EPA Substance Registry System: 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride(358721-54-7)

Safety Data

• Hazardous Substances Data: 358721-54-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride is used as an intermediate for the synthesis of various pharmaceuticals. Its unique structure and functional group contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride is employed as an intermediate in the production of agrochemicals. Its versatility allows for the creation of compounds that can be used in pest control and crop protection.
Used in Organic Synthesis:
3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride is used as a reagent in organic synthesis. Its propanoyl chloride functional group facilitates the formation of various organic compounds, making it a valuable component in the synthesis of complex molecules.
Used in the Preparation of Esters and Amides:
3-(3,5-Dimethylisoxazol-4-yl)propanoyl chloride also serves as a precursor in the preparation of esters and amides. Its ability to form these functional groups makes it an essential component in the synthesis of a wide range of chemical products.

Upstream product

• 123-54-6 acetylacetone 
• 154928-90-2 Methyl β-(3,5-dimethyl-4-isoxazolyl)propionate 
• 13984-53-7 methyl 4-acetyl-5-oxohexanoate 
• 116423-07-5 β-(3,5-Dimethyl-4-isoxazolyl)propionic acid 

Downstream Products

• 358721-52-5 3-(3,5-Dimethyl-4-isoxazolyl)-N-(4-fluoro-3-methylphenyl)propanamide 

Relevant articles and documents

Compounds useful in therapy

Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: X represents —[CH2]a—R or —[CH2]a—O—[CH2]b—R; a represents a number selected from 0 to 6; b represents a number selected from 0 to 6; R represents H, CF3 or Het; Het represents an optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic ring; Y represents one or more substituents independently selected from —[O]c—[CH2]d—R1, which may be the same or different at each occurrence; c at each occurrence independently represents a number selected from 0 or 1; d at each occurrence independently represents a number selected from 0 to 6; R1 at each occurrence independently represents H, halo, CF3, CN or Het1; Het1 at each occurrence independently represents a 5- or 6-membered unsaturated heterocyclic ring; V represents a direct link or —O—; Ring A represents an optionally substituted 5- to 7-membered saturated heterocyclic ring, or a phenylene group; Q represents a direct link or —N(R2)—; R2 represents hydrogen or C1-6 alkyl; Z represents —[O]e—[CH2]f—R3, a phenyl ring (optionally fused to a benzene ring or Het2, and the group as a whole being optionally substituted), or Het3 (optionally fused to an benzene ring or Het4, and the group as a whole being optionally substituted); R3 represents C1-6 alkyl (optionally substituted), C3-6 cycloalkyl, C3-6 cycloalkenyl, phenyl (optionally substituted), Het5 or NR4R5; e represents a number selected from 0 or 1; f represents a number selected from 0 to 6; Het2 and Het5 independently represent optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic rings; Het3 represents an optionally substituted 4 to 6-membered saturated, partially saturated or aromatic heterocyclic ring; Het4 represents an optionally substituted 6-membered aromatic heterocyclic ring; R4 and R5 independently represent optionally substituted C1-6 alkyl, C1-6 alkyloxy, C3-8 cycloalkyl (optionally fused to C3-8 cycloalkyl), Het6, or hydrogen; Het6 represents an optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic ring; are useful for treating a disorder for which a V1a antagonist is indicated.