3589-59-1

Basic information

• Product Name: N-(4-Nitrophenyl)glycine ethyl ester
• Synonyms: N-(4-Nitrophenyl)glycine ethyl ester
• CAS NO: 3589-59-1
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.2133
• Mol File: 3589-59-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 361.6°Cat760mmHg
• Flash Point: 172.5°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 2.05E-05mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: N-(4-Nitrophenyl)glycine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Nitrophenyl)glycine ethyl ester(3589-59-1)
• EPA Substance Registry System: N-(4-Nitrophenyl)glycine ethyl ester(3589-59-1)

Safety Data

• Hazardous Substances Data: 3589-59-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12N2O4/c1-2-16-10(13)7-11-8-3-5-9(6-4-8)12(14)15/h3-6,11H,2,7H2,1H3

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 100-01-6 4-nitro-aniline 
• 3598-91-2 N-(4-nitrophenyl)bromoacetamide 
• 300558-35-4 2-(4-tert-butylphenoxy)-N-(4'-nitrophen-1'-yl)acetamide 
• 105-36-2 ethyl bromoacetate 

Relevant articles and documents

Copper-Catalyzed Annulation of Oxime Acetates with α-Amino Acid Ester Derivatives: Synthesis of 3-Sulfonamido/Imino 4-Pyrrolin-2-ones

A copper-catalyzed annulation of oxime acetates and α-amino acid ester derivatives for the easy preparation of 4-pyrrolin-2-ones bearing a 3-amino group has been developed. This process features the oxidation of amines with oxime esters as the internal oxidant to produce the active 1,3-dinucleophilic and 1,2-dielectrophilic species concurrently. The subsequent nucleophilic cyclization realizes the efficient construction of 4-pyrrolin-2-one derivatives.

Dual role of Cu2O nanocubes as templates and networking catalysts for hollow and microporous Fe-porphyrin networks

Cu2O nanocubes were used for the synthesis of hollow and microporous Fe porphyrin networks (H-MFePN). In this synthesis, Cu2O nanocubes performed not only as networking catalysts but also as shape controlling templates. MFePN were formed on the surface of the Cu2O nanocubes through azide-alkyne cycloaddition of tetrakis(4-ethynylphenyl) Fe-porphyrin with 1,4-diazidobenzene. H-MFePN showed excellent catalytic activities in carbene insertion into N-H bonds, maintaining their activities during five recycle tests.

Reactivity of Me-pma RhI and IrI Complexes upon Deprotonation and Their Application in Catalytic Carbene Carbonylation Reactions

Dehydrogenative oxidation of amines is a relevant process in metal-mediated catalysis, with the amines being either substrates or ligands. Transformation of amine- into imine-type ligands in the coordination sphere of a transition metal can be an important catalyst activation process. The behaviour of secondary pyridin-2-ylmethanamine (pma) ligands in the corresponding rhodium and iridium complexes upon NH deprotonation varies, depending on a number of factors. In this paper the behaviour of the Me-pma ligand [Me-pma = N-methyl-1-(pyridin-2-yl)methanamine] bound to [Rh(cod)]+ and [Ir(cod)]+ was studied. Whereas the iridium amido complex could be obtained upon NH deprotonation, the rhodium complex instantaneously disproportionated into a free pma ligand and an unusual dinuclear complex, adopting a structure with two RhI metal centres hosted by a dianionic (pma-2H)2- ligand, and with the ligand coordinating to Rh2 as an "aza-allyl" fragment. The study gives further proof for the effect of pyridine ligation on the previously observed charge-transfer from the ligand to the metal. Furthermore, the catalytic activity of both the Ir and the Rh species with Me-pma in carbene carbonylation reactions to generate ketenes was studied.