35896-47-0

Upstream product

• 35896-42-5 silver trifluoromethanesulfinate 
• 70-11-1 α-bromoacetophenone 
• 2926-29-6 Langlois reagent 
• 3282-32-4 2-diazo-acetophenone 
• 41804-89-1 potassium triflinate 

Relevant academic research and scientific papers

Rapid Interception of CnF2n+1(O)SO. Radical with Copper-Based Carbene: A Novel Access to Perfluoroalkanesulfinate Ester

In this communication, an unprecedented interception of CnF2n+1(O)SO. radical with a copper-based carbene has been established. Distinguished by wide substrate scopes and mild reaction conditions, this novel radical–carbene coupling reaction (RCC reaction) provides a fundamentally different and mechanistically interesting strategy for the synthesis of perfluoroalkanesulfinate esters.

METHOD FOR PREPARING PERFLUOROALKYL SULFINATE ESTER

The present invention discloses a method for preparing a perfluoroalkyl sulfinate ester. The method includes reacting an α-carbonyldiazo compound and a sodium perfluoroalkyl sulfinate, in an organic solvent, in the presence of anhydrous copper acetate as an optimal catalyst and tert-butyl hydroperoxide (TBHP) as a green oxidant, to obtain the perfluoroalkyl sulfinate ester. Compared to the prior art, the present method has the advantages of a wide range of reaction substrates, a short reaction time, a high reaction yield, and mild reaction conditions. The reaction does not require pre-activation of sodium perfluoroalkyl sulfinate, which can participate in the reaction directly, making reaction operations simple. The present method uses TBHP as a green oxidant and produces tert-butanol and water after reaction. Moreover, the present method avoids using a bromide or a chloride as a reaction material, and thus avoids formation of a large amount of a halide salt.

Method for preparing perfluoroalkyl sulfinic acid ester

The invention discloses a method for preparing a perfluoroalkyl sulfinic acid ester. The method comprises the steps of adopting an alpha-carbonyl diazo compound and perfluoro sodium alkylsulfinate asreaction substrates, adopting cheap cupric acetate anhydrous as an optimal catalyst, adopting t-butylhydroperoxide (TBHP) as a green oxidizing agent, and carrying out coupling reaction in an organic solvent to obtain the perfluoroalkyl sulfinic acid ester. Compared with the prior art, the method provided by the invention has the following advantages of wide reaction substrate range, short reactiontime, higher reaction yield, and mild reaction conditions and the like. The reaction can be operated more simply since the perfluoro sodium alkylsulfinate can be directly reacted instead of being pre-activated; according to the method provided by the invention, the TBHP is used as the green oxidizing agent and is reacted to generate tertiary butanol and water, and meanwhile, bromide or chloride is prevented from being used as a reaction raw material, so that the formation of a large number of halide salt is avoided, the environment cannot be harmed, and the requirement of modern green chemistry is met.