358969-71-8 Usage
Uses
Used in Pharmaceutical Industry:
4-AMINO-1-N-ALLOC-PIPERIDINE is used as a reactant for the preparation of 4-aminopiperidine analogs, which are important in the development of various pharmaceutical compounds. These analogs have potential applications in the treatment of a wide range of medical conditions, including neurological disorders, cardiovascular diseases, and various types of cancer. The unique structure of 4-AMINO-1-N-ALLOC-PIPERIDINE allows for the synthesis of a diverse array of analogs with different biological activities, making it a valuable tool in the search for new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 358969-71-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,8,9,6 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 358969-71:
(8*3)+(7*5)+(6*8)+(5*9)+(4*6)+(3*9)+(2*7)+(1*1)=218
218 % 10 = 8
So 358969-71-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H16N2O2/c1-2-7-13-9(12)11-5-3-8(10)4-6-11/h2,8H,1,3-7,10H2
358969-71-8Relevant academic research and scientific papers
Fernández-Forner, Dolors,Casals, Gaspar,Navarro, Eloísa,Ryder, Hamish,Albericio, Fernando
, p. 4471 - 4474 (2001)
A useful method for Alloc removal from secondary amines on solid-phase has been optimised. The use of Me2NH·BH3 (40 equiv., 40 min) as scavenger of the allyl cations in a palladium-catalysed process with Pd[PPh3]4 leads to quantitative removal of the Alloc group without any allyl back alkylation. Other scavengers such as morpholine or PhSiH3 are clearly inferior. Furthermore, this study has highlighted differences in the reaction kinetics of the deprotection step between secondary and primary amines such as those from α-amino acids.
