359-14-8 Usage
Uses
Used in Pharmaceutical Production:
Chloroacetyl fluoride is used as a key intermediate in the synthesis of various pharmaceuticals. Its ability to introduce the acetyl group into compounds makes it a valuable component in the development of drugs with specific therapeutic properties.
Used in Pesticide Manufacturing:
In the agricultural industry, chloroacetyl fluoride serves as an essential precursor in the production of certain pesticides. Its role in creating effective pest control agents contributes to crop protection and increased agricultural yields.
Used in Organic Synthesis:
Chloroacetyl fluoride is employed as a reagent in organic synthesis reactions across different chemical industries. Its capacity to acetylate a wide range of compounds facilitates the creation of new organic molecules for various applications, including the development of new materials and the improvement of existing products.
Safety Considerations:
Given its high toxicity and potential to cause severe irritation, chloroacetyl fluoride must be handled with extreme caution. Strict safety protocols, including the use of personal protective equipment and proper training for those working with the compound, are essential to minimize risks and ensure the safety of personnel and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 359-14-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 359-14:
(5*3)+(4*5)+(3*9)+(2*1)+(1*4)=68
68 % 10 = 8
So 359-14-8 is a valid CAS Registry Number.
359-14-8Relevant academic research and scientific papers
Nucleophilic Substitution Reactions at Chloro-Substituted Ozonides and at a Chlorinated Dimeric Peroxide
Griesbaum, Karl,Schlindwein, Konrad
, p. 8062 - 8066 (2007/10/03)
Reactions of substituted 3-chloro- (2a-4a) and 3,5-dichloro-1,2,4-trioxolanes (9a, 10a) with AgBF4 in the presence of LiF gave the corresponding fluoro-substituted ozonides (2b - 4b and 9b and 10b).Substitutions of some of these chlorinated ozonides by the methoxy and by the acetoxy groups, and of 3,6-dichloro-3,6-dimethyl-1,2,4,5-tetroxane (22a) with the acetoxy group have been achieved too.
Synthesis of Halogenated Esters of Fluorinated Carboxylic Acids by the Regio- and Stereospecific Addition of Acyl Hypochlorites to Olefins
Tari, Isao,DesMarteau, Darryl D.
, p. 1214 - 1217 (2007/10/02)
Addition reactions of the fluorinated acyl hypochlorites CF3CO2Cl, C2F5CO2Cl, n-C3F7CO2Cl, ClCF2CO2Cl, and HCF2CO2Cl with CF2=CF2 and CF2=CH2 form the respective esters in varying yields.The reactions are regiospecific with CF2=CH2.Additional reactions of CF3CO2Cl with CF2=CFCl, CF2=CCl2, CH2=CH2, and cis- and trans-CFH=CFH further illustrate the potential of the acyl hypochlorites for the synthesis of a variety of esters.In addition, the latter reactions provide further examples of the regiospecificity of these additions and two examples of their stereospecificity.A concerted cis addition is proposed.The new esters exhibit excellent thermal stability, but are unstable in the presence of KF.
