453-12-3 Usage
Functional groups
Ketone, Chlorine atom, Fluorine atom
Structure
Chlorine atom bonded to the first carbon, fluorine atom bonded to the third carbon, and a carbonyl group bonded to the second carbon
Applications
Organic synthesis, medicinal chemistry, building block for pharmaceuticals and other chemicals
Potential uses
Solvent, reagent in chemical reactions
Factors affecting properties and uses
Purity, concentration, and intended application
Check Digit Verification of cas no
The CAS Registry Mumber 453-12-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 453-12:
(5*4)+(4*5)+(3*3)+(2*1)+(1*2)=53
53 % 10 = 3
So 453-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H4ClFO/c4-1-3(6)2-5/h1-2H2
453-12-3Relevant articles and documents
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Chaabouni,Baklouti
, p. 227 - 233 (1990)
The synthesis of F-alkyl and Cl-alkyl monofluoromethyl ketones has been achieved by oxidation of the homologous alcohols under phase-transfer conditions using Na2Cr2O7/H2SO4 in methylene chloride in t
ORGANIC COMPOUNDS
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Page/Page column 84, (2010/04/06)
The present invention relates to a compound of formula (I) (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.