35932-10-6Relevant academic research and scientific papers
Inhibitory effect of acylphloroglucinol derivatives on the replication of vesicular stomatitis virus.
Chiba,Takakuwa,Tada,Yoshii
, p. 1769 - 1772 (2007/10/02)
The antiviral activity of natural phloroglucinols and of synthesized mono- and diacylphloroglucinols, and 2,6-diacyl-4,4-dialkylcyclohexa-1,3,5-triones was investigated. A correlation between the acyl chain length and inhibitory activity against vesicular stomatitis virus (VSV) was observed. Potent antiviral activity was found in di-isovalerylphoroglucinol. 2,6-Diacyl-4,4-dialkylcyclohexa-1,3,5-triones inhibited replication of the virus with low cytotoxicity.
Analogues of natural phloroglucinols as antagonists against both thromboxane A2 and leukotriene D4
Tada,Chiba,Takakuwa,Kojima
, p. 1209 - 1212 (2007/10/02)
Antagonists against both thromboxane A2 and leukotriene D4 were prepared from phloroglucinol. These compounds showed almost the same activity as the chinesins which were isolated from Hypericum chinense L. The correlation between the
