359414-53-2Relevant academic research and scientific papers
Montmorillonite clay-catalyzed one-pot synthesis of α-amino phosphonates
Yadav,Subba Reddy,Madan
, p. 1131 - 1133 (2001)
α-Aminophosphonates are synthesized by three component condensation of aldehydes, amines and diethyl phosphite using montmorillonite KSF under microwave irradiation in solvent-free conditions to afford enhanced yields and reduced reaction times compared t
Inhibitors of phenylalanine ammonialyase: 1-aminobenzylphosphonic acids substituted in the benzene ring
Zoń, Jerzy,Amrhein, Nikolaus,Gancarz, Roman
, p. 9 - 21 (2007/10/03)
Dextrorotatory 1-amino-3′,4′-dichlorobenzylphosphonic acid was found to be a potent inhibitor of the plant enzyme phenylalanine ammonia-lyase both in vitro and in vivo from among the ring-substituted 1-aminobenzylphosphonic acids and other analogues of phenylglycine. A structure activity relationship analysis of the results obtained permits predictions on the geometry of the pocket of the enzyme and is a basis in the strategy of better inhibitor synthesis.
