359443-54-2

Basic information

• Product Name: ethyl 3,4-diphenyl-6-(4-toluidino)pyrido[2',3':4,5]thieno[2,3-c]pyridazine-7-carboxylate
• Synonyms: ethyl 3,4-diphenyl-6-(4-toluidino)pyrido[2',3':4,5]thieno[2,3-c]pyridazine-7-carboxylate
• CAS NO: 359443-54-2
• Molecular Formula: C31H24N4O2S
• Molecular Weight: 516.61286
• Mol File: 359443-54-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 3,4-diphenyl-6-(4-toluidino)pyrido[2',3':4,5]thieno[2,3-c]pyridazine-7-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3,4-diphenyl-6-(4-toluidino)pyrido[2',3':4,5]thieno[2,3-c]pyridazine-7-carboxylate(359443-54-2)
• EPA Substance Registry System: ethyl 3,4-diphenyl-6-(4-toluidino)pyrido[2',3':4,5]thieno[2,3-c]pyridazine-7-carboxylate(359443-54-2)

Safety Data

• Hazardous Substances Data: 359443-54-2(Hazardous Substances Data)

Upstream product

• 622-58-2 p-Tolylisocyanate 
• 211569-42-5 6-(2-ethoxycarbonylvinyl)-3,4-diphenyl-5-[(triphenylphosphoraniliden)amino]thieno[2,3-c]pyridazine 

Relevant articles and documents

Iminophosphoranes in heterocyclic chemistry. A simple one-pot synthesis of pyridothienopyridazines and pyrimidothienopyridazines

Iminophosphoranes, 6-(2-ethoxycarbonylvinyl)-3,4-diphenyl-5-[(triphenylphosphoranylidene) amino]thieno[2,3-c]pyridazine 1a, 6-(2-cyanovinyl)-3,4-diphenyl-5-[(triphenylphosphoranylidene)amino]thieno [2,3-c]pyridazine 1b, and 6-(4-aryliminomethylene)-3,4-diphenyl-5-[(triphenylphosphoranylidene) amino]thieno[2,3-c] pyridazine 5a-c react with heterocumulenes such as iso(thio)cyanates, carbon dioxide and carbon disulfide to give directly the title compounds in an aza-Wittig/electrocyclic-ring closure process. The N-heteroaryliminophosphoranes 8a,b underwent an unusual pyridine ring closure under Vilsmeier conditions to form the pyridothienopyridazines 10a,b.