35949-22-5Relevant academic research and scientific papers
Enantiospecific syntheses of the potent bioactives nagilactone F and the mould metabolite LL-Z1271α an evaluation of their allelopathic potential
Barrero, Alejandro F.,Sanchez, Juan F.,Elmerabet, Jamal,Jimenez-Gonzalez, David,Macias, Francisco A.,Simonet, Ana M.
, p. 7289 - 7304 (1999)
Improved syntheses are described for nagilactone F and the antibiotic LL-Z1271α, two of the most potent bioactive members of the podolactone family. The allelopathic potential of some members of this podolactone series has been evaluated, with the result
Total synthesis of oidiodendrolides and related norditerpene dilactones from a common precursor: Metabolites CJ-14,445, LL-Z1271γ, oidiolactones A, B, C, and D, and nagilactone F
Hanessian, Stephen,Boyer, Nicolas,Reddy, Gone Jayapal,Deschenes-Simard, Benoit
supporting information; experimental part, p. 4640 - 4643 (2009/12/09)
An efficient, high-yielding strategy has been developed for the asymmetric total synthesis of seven norditerpenoid dilactones known for their diverse biological properties. The three key steps employed to obtain a tricyclic lactone intermediate involved a
An Efficient Synthesis of the Antifungal Dilactone LL-Z1271α and of other Biologically Active Compounds
Barrero, Alejandro F.,Sanchez, Juan F.,Elmerabet, Jamal
, p. 5251 - 5254 (2007/10/02)
The syntheses of the terpenoid antifungal LL-Z1271α and other related compounds were achieved starting from the communic acids.The synthetic approach includes a mercuriation-demercuriation reaction of a γ,δ-unsaturated methyl ester in the presence of O2, giving rise to a lactone ring.
