35969-54-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Ethoxynicotinic acid is used as a building block for the synthesis of various pharmaceutical drugs, contributing to the development of new medications and therapies.
Used in Pesticide Production:
In the agricultural sector, 2-ethoxynicotinic acid is used in the production of pesticides, herbicides, and fungicides, helping to protect crops from pests and diseases.
Used in Antioxidant Research:
2-Ethoxynicotinic acid is being researched for its antioxidant properties, with potential applications in the prevention and treatment of oxidative stress-related conditions.
Used in Neuroprotective Therapy:
Owing to its neuroprotective potential, 2-ethoxynicotinic acid is under investigation for use in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's, where it may help protect and preserve neuronal function.

InChI:InChI=1/C8H9NO3/c1-2-12-7-6(8(10)11)4-3-5-9-7/h3-5H,2H2,1H3,(H,10,11)

Upstream product

• 2942-59-8 2-chloronicotinic acid 
• 64-17-5 ethanol 

Downstream Products

• 393184-78-6 5-bromo-2-ethoxynicotinic acid 
• 335078-07-4 2-ethoxy-5-iodopyridine-3-carboxylic acid 
• 15441-51-7 2-Ethoxypyridine-3-carboxylic Acid Ethyl Ester 
• 68359-07-9 5-chloro-2-ethoxynicotinic acid 

Relevant academic research and scientific papers

Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-ones and intermediates thereof

A process is provided for the preparation of compounds of formula (I) herein comprising reacting a compound of formula (II), (III), (IV) or (V) in the presence of-OR3 and a hydroxide trapping agent or in the case of compounds of formula (IV) reacting in the presence of an auxiliary base and a hydroxide trapping agent (i.e.-OR3 is substituted by the auxiliary base), wherein X is a leaving group and R1 to R4 are as defined.

Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction

Compounds of the formulae (IA) and (IB): wherein R1is C1to C3alkyl optionally substituted with phenyl, Het or a N-linked heterocyclic group selected from piperidinyl and morpholinyl; wherein said phenyl group is optionally substituted by one or more substitutents selected from C1to C4alkoxy; halo; CN; CF3; OCF3or C1to C4alkyl wherein said C1to C4alkyl group is optionally substituted by C1to C4haloalkyl or haloalkoxy either of which is substituted by one or more halo atoms; R2is C1to C6alkyl and R13is OR3or NR5R6, or pharmaceutically or veterinarily acceptable salts thereof, or pharmaceutically or veterinarily acceptable solvates of either entity are potent and selective inhibitors of type 5 cyclic guanosine 3′,5′-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).

AN IMPROVED METHOD OF CHLORINATING 2-ALKOXYNICOTINIC ACIDS

A novel chlorination process for preparing 5-chloro-2-alkoxynicotinic acids has been developed using commercial 5.25percent sodium hypochlorite (Clorox) as a chlorinating agent.

Hypoglycemic 5-substituted oxazolidine-2,4-diones

Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.