35976-97-7Relevant academic research and scientific papers
A convenient 'catch and release' synthesis of fused 2-alkylthio-pyrimidinones mediated by polymer-bound BEMP
Adams, Gregory L.,Graybill, Todd L.,Sanchez, Robert M.,Magaard, Victoria W.,Burton, George,Rivero, Ralph A.
, p. 5041 - 5045 (2003)
A robust 'catch and release' synthesis of fused 2-alkylthio-3-substituted-pyrimidinones mediated by the polymer-bound base P-BEMP is described. This reengineered synthesis combines the efficiency of the classical synthesis (three steps, three diversity points) with the practical benefits of resin-bound reagents. The solution-phase strategy, reagent compatibility, and the results of a representative 48-member combinatorial library are described and presented herein.
One-pot, simple, and convenient synthesis of 2-Thioxo-2,3- dihydroquinazolin-4(1H)-ones
Tiwari, Vinod K.,Singh, Desh D.,Hussain, Hakkim A.,Mishra, Bhuwan B.,Singh, Archana
, p. 43 - 48 (2008/09/20)
A simple and convenient method for the synthesis of diverse 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones was developed as one-pot reaction of anthranilic acid esters, primary amines, and bis(benzotriazolyl)methanethione in presence of the amidine base DBU.
