359763-06-7Relevant academic research and scientific papers
A new efficient synthetic strategy for N-(dialkylamino)azacycle as a tetrasubstituted hydrazine derivative using sodium triacyloxyborohydride
Mizufune, Hideya,Yamamoto, Hiroaki,Nakamura, Minoru,Miki, Shokyo
, p. 6275 - 6280 (2008/09/21)
A new efficient and convergent method has been developed to construct a N-(dialkylamino)azacyclic system as a tetrasubstituted hydrazine via reductive alkylation of the corresponding hydrazone using sodium triacyloxyborohydride [NaBH(OCOR)3], which is tolerant of various substituents (e.g., phenol, conjugated olefin, amide, and thioamide) on the substrate and useful for organization of the N-aminoazacycle array.
