359766-31-7Relevant articles and documents
Total synthesis of nafuredin, a selective NADH-fumarate reductase inhibitor.
Takano,Nagamitsu,Ui,Shiomi,Yamaguchi,Masuma,Kuwajima,Omura
, p. 2289 - 2291 (2007/10/03)
[structure: see text] Total synthesis of nafuredin, a selective NADH-fumarate reductase inhibitor, has been accomplished by a convergent approach. The C1-C8 and C9-C18 segments were derived efficiently from D-glucose and (S)-(-)-2-methyl-1-butanol, respectively, coupled by stereoselective Julia olefination, and converted to nafuredin.