35978-33-7

Basic information

• Product Name: ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE
• Synonyms: 2-AMINO-4-(4-FLUORO-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER;3-THIOPHENECARBOXYLIC ACID, 2-AMINO-4-(4-FLUOROPHENYL)-, ETHYL ESTER;AKOS MSC-0436;AKOS BBS-00000846;IFLAB-BB F0307-0495;ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE;AURORA 20700;BUTTPARK 47\15-16
• CAS NO: 35978-33-7
• Molecular Formula: C₁₃H₁₂FNO₂S
• Molecular Weight: 265.3
• EINECS: 200-417-5
• Mol File: 35978-33-7.mol

Chemical Properties

• Melting Point: 92-95°C
• Boiling Point: 388.7 °C at 760 mmHg
• Flash Point: 188.9 °C
• Appearance: yellow solid
• Density: 1.293
• Vapor Pressure: 3E-06mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE(35978-33-7)
• EPA Substance Registry System: ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE(35978-33-7)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 35978-33-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE is used as a research compound for investigating the structure-activity relationship of novel tissue transglutaminase inhibitors. This application is crucial in the development of new drugs and therapies targeting tissue transglutaminase, an enzyme involved in various physiological processes and diseases.
Used in Drug Development:
In the drug development industry, ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE serves as a key compound in the design and synthesis of potential tissue transglutaminase inhibitors. Its unique chemical properties allow researchers to explore new avenues in the treatment of diseases associated with the dysregulation of tissue transglutaminase activity.
Used in Chemical Synthesis:
ETHYL 2-AMINO-4-(4-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE is also utilized as an intermediate in the synthesis of various organic compounds and pharmaceuticals. Its versatile chemical structure enables the creation of a wide range of molecules with diverse applications in the chemical and pharmaceutical industries.

InChI:InChI=1/C13H12FNO2S/c1-2-17-13(16)11-10(7-18-12(11)15)8-3-5-9(14)6-4-8/h3-7H,2,15H2,1H3

Upstream product

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• 105-56-6 ethyl 2-cyanoacetate 
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Downstream Products

• 546116-60-3 C₁₆H₁₃FN₂O₃S 
• 384351-45-5 4-chloro-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine 
• 1181227-94-0 3-{[5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid 
• 935760-47-7 ethyl 5-(4-fluorophenyl)-4-oxo-3,4-dihydrothieno[2,3-d]-pyrimidine-2-carboxylate 
• 935759-60-7 5-(4-fluorophenyl)-4-oxo-N-{3-[2-(1H-1,2,4-triazol-3-yloxy)-ethoxy]benzyl}-3,4-dihydro-thieno[2,3-d]pyrimidine-2-carboxamide 
• 1176727-50-6 C₁₆H₁₂FN₃OS 
• 1002275-30-0 C₁₅H₁₀FN₃OS 
• 1018577-22-4 C₁₆H₁₃FN₂O₃S 
• 1018307-56-6 C₁₅H₁₁FN₂O₃S 
• 1056054-66-0 2-methyl-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine-4(3H)-one 
• 1391981-88-6 N-(5-(2-chlorobenzoyl)-4-(4-fluorophenyl)thiophen-2-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 
• 1391982-12-9 2-(4-(ethylsulfonyl)phenyl)-N-(4-(4-fluorophenyl)thiophen-2-yl)acetamide 
• 1176046-43-7 4-(4-fluorophenyl)thiophen-2-amine 
• 1391981-95-5 2-[4-(ethylsulfonyl)phenyl]-N-[4-(4-fluorophenyl)-5-(phenylcarbonyl)-2-thienyl]acetamide 

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