3598-60-5

Basic information

• Product Name: 4-(Phthalimidyl)butanal
• Synonyms: 4-(Phthalimidyl)butanal;4-Phthalimidylbutyraldehyde;N-(3-Formylpropyl)phthalimide;4-[1,3-bis(oxidanylidene)isoindol-2-yl]butanal;4-phthalimidobutyraldehyde;4-(1,3-Diketoisoindolin-2-Yl)Butyraldehyde;4-(1,3-Dioxo-2-Isoindolinyl)Butanal;4-(1,3-Dioxoisoindol-2-Yl)Butanal 4-(1,3-Dioxoisoindolin-2-Yl)Butanal
• CAS NO: 3598-60-5
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.23
• Mol File: 3598-60-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 373.9°Cat760mmHg
• Flash Point: 173.7°C
• Appearance: /
• Density: 1.274g/cm³
• Vapor Pressure: 8.67E-06mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 4-(Phthalimidyl)butanal(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Phthalimidyl)butanal(3598-60-5)
• EPA Substance Registry System: 4-(Phthalimidyl)butanal(3598-60-5)

Safety Data

• Hazardous Substances Data: 3598-60-5(Hazardous Substances Data)

Usage

General Description

4-(Phthalimidyl)butanal is a chemical compound with the molecular formula C12H11NO2. It is a derivative of phthalimide and has a butanal group attached to it. 4-(Phthalimidyl)butanal is used in organic synthesis and can be a key intermediate in the production of pharmaceuticals, dyes, and agricultural chemicals. It is a white to off-white solid that is sparingly soluble in water and is mostly used in research and development processes. It is important to handle this compound with care as it may have potential health hazards and should be used in a well-ventilated area, and with the appropriate personal protective equipment.

InChI:InChI=1/C12H11NO3/c14-8-4-3-7-13-11(15)9-5-1-2-6-10(9)12(13)16/h1-2,5-6,8H,3-4,7H2

Upstream product

• 83179-86-6 2-(buta-2,3-dien-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione 
• 100-51-6 benzyl alcohol 
• 85-44-9 phthalic anhydride 
• 10314-06-4 4-phthalimidobutyryl chloride 

Downstream Products

• 1026634-99-0 4-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propyl]-6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 146548-64-3 [1-{[(S)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-phosphonic acid diphenyl ester 
• 113953-96-1 Boc->Cad<-Pua(Z)=Pht 
• 121903-75-1 Pht=Pua(Z)-OH 
• 929282-38-2 (3R)-3-{[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]amino}-N-phenyl-1-piperidinecarboxamide 
• 558444-72-7 (S)-2-[4-(5,6,7,8-tetrahydro-quinolin-8-ylamino)-butyl]-isoindole-1,3-dione 
• 15741-71-6 N-phthalimidotryptamine 
• 1347655-26-8 C₂₆H₂₈F₂N₂O₆ 
• 1621071-18-8 2-(4-hydroxy-4-(5-methyl-2-nitrophenyl)butyl)isoindoline-1,3-dione 
• 3130-75-4 4-phthalimidobutyric acid 
• 95711-01-6 [1-(Benzhydryl-amino)-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-phosphinic acid 
• 176982-87-9 2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-hydroxy-2-morpholin-4-yl-hexanenitrile 
• 20820-73-9 1,4-diaminobutylphosphonic acid 
• 74510-02-4 1-Phenyl-7-phthalimido-1,4-heptandion 

Relevant articles and documents

Precious metal complexes of bis(pyridyl)allenes: Synthesis and catalytic and medicinal applications

The incorporation of donor-type substituents on the allene core opens up the possibility of coordination complexes in which the metal is bonded to the donor groups, with or without interaction with the double bond system. Despite the challenges in the syn

A THERANOSTIC PROBE AND ITS USE FOR TARGETING AND/OR LABELING THE EGFR KINASE AND/OR THE CELLS EXPRESSING EGFR OR ITS FAMILY MEMBERS

The present application is directed to a theranostic probe and its use for targeting and/or labeling the EGFR kinase and/or the cells expressing EGFR or its family members.

Synthesis of Vinyl Isocyanides and Development of a Convertible Isonitrile

The reaction of isocyanomethylenetriphenylphosphorane, generated in situ from the corresponding phosphonium salt, with a diverse set of aldehydes afforded vinyl isocyanides in good to high yields. Excellent E-selectivity was observed for aliphatic aldehydes and 2,6-disubstituted aromatic aldehydes, whereas Z-olefins were formed predominantly with ortho-substituted aryl aldehydes. (Z)-1-Bromo-2-(2-isocyanovinyl)benzene (5l) was found to be a truly universal isonitrile since, after Ugi reaction, the resulting secondary amide unit (RNHCO-) is convertible under both acidic and basic conditions. The application of 5l in the synthesis of polyheterocycles is also illustrated.