35982-93-5

Basic information

• Product Name: 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl-
• Synonyms: 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl-;1,2-dihydro-2-oxo-5-phenyl-3-pyridinecarbonitrile;2-Hydroxy-5-phenyl-nicotinonitrile
• CAS NO: 35982-93-5
• Molecular Formula: C₁₂H₈N₂O
• Molecular Weight: 196.20472
• EINECS: -0
• Mol File: 35982-93-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 416.4°Cat760mmHg
• Flash Point: 205.7°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 3.82E-07mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl-(35982-93-5)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl-(35982-93-5)

Safety Data

• Hazardous Substances Data: 35982-93-5(Hazardous Substances Data)

Usage

General Description

3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-5-phenyl- is a chemical compound with the molecular formula C12H9N3O. It is a dihydropyridine derivative and a nitrile compound. This chemical is often used in the synthesis of pharmaceuticals and other organic compounds. Its structure contains a pyridine ring, a nitrile group, and a phenyl group, making it a versatile building block in organic chemistry. It has also been studied for its potential biological activities and pharmacological properties.

InChI:InChI=1/C12H8N2O/c13-7-10-6-11(8-14-12(10)15)9-4-2-1-3-5-9/h1-6,8H,(H,14,15)

Upstream product

• 882029-80-3 p-toluenesulfonic acid 3,5-dibromo(pyridin-2-yl) ester 
• 7089-34-1 ((E)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 107-91-5 cyanoacetic acid amide 
• 67382-50-7 3-dimethylamino-2-phenylpropenal 
• 103-82-2 phenylacetic acid 
• 7089-34-1 ((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 

Downstream Products

• 10177-10-3 5-phenyl-2-chloropyridine-3-carbonitrile 
• 10177-08-9 1,2-dihydro-2-oxo-5-phenyl-3-pyridinecarboxylic acid 

Relevant articles and documents

Reaction mechanism of vinamidinium salts and cyanoacetamide derivatives

The mechanism of formation of a pyridin-2(1H )-one synthesised from vinamidinium salts and cyanoacetamide derivatives is illustrated through the preparation and characterisation of a key intermediate.

Design, synthesis and structure-activity relationship studies of morpholino-1H-phenalene derivatives that antagonize Mcl-1/Bcl-2

We report herein characteristic studies of Mcl-1 and Bcl-2 dual inhibitors. It was found that a protruding carbonyl group forming hydrogen bond with R263 plays a predominant role compared with the hydrophobic group that occupies the p2 pocket. A series of dual inhibitors representing different parts of the morpholino-1H-phenalene were designed, synthesized and evaluated.

Substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyridines

This disclosure describes novel substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridines and their use as agents for treating anxiety.