10177-08-9 Usage
Description
2-Hydroxy-5-phenylnicotinic acid is a chemical compound with the molecular formula C12H9NO3, belonging to the nicotinic acid derivatives. It features a hydroxyl group and a phenyl group attached to the pyridine ring, endowing it with potential biological activities and making it a versatile compound with promising pharmacological properties.
Uses
Used in Pharmaceutical Research:
2-Hydroxy-5-phenylnicotinic acid is used as a research compound for its potential biological activities, including its role as an inhibitor of quinoline oxidoreductase and a potential anti-tumor agent. Its unique structure and properties make it a valuable candidate for the development of new drugs and therapies.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Hydroxy-5-phenylnicotinic acid is used as a key intermediate for the synthesis of various complex organic molecules and pharmaceuticals. Its presence of functional groups allows for versatile chemical reactions and modifications, facilitating the creation of new compounds with desired properties.
Used in Neurodegenerative Disease Treatment:
2-Hydroxy-5-phenylnicotinic acid is studied for its potential application in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Its pharmacological properties suggest that it may have neuroprotective effects and contribute to the development of therapeutic strategies for these debilitating conditions.
Overall, 2-Hydroxy-5-phenylnicotinic acid is a multifaceted chemical with applications spanning across pharmaceutical research, organic synthesis, and neurodegenerative disease treatment, highlighting its significance in the scientific and medical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 10177-08-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,7 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10177-08:
(7*1)+(6*0)+(5*1)+(4*7)+(3*7)+(2*0)+(1*8)=69
69 % 10 = 9
So 10177-08-9 is a valid CAS Registry Number.
10177-08-9Relevant articles and documents
New synthetic routes to 3-, 5-, and 6-aryl-2-chloropyridines
Church,Trust,Albright,Powell
, p. 3750 - 3758 (2007/10/02)
The efficient synthesis of 3-, 5-, and 6-aryl-2-chloropyridines via the facile preparation of 5-(dimethylamino)aryl-substituted pentadienyl nitriles and cyclization with hydrochloric acid is described. This approach allows for the introduction of other electron-withdrawing substituents on the pyridine ring as well as the preparation of the desired unsubstituted arylpyridines. Some differences in the rates of cyclization of the pentadienyl nitriles as well as the yields of chloropyridines were observed that depended on the position and degree of substitution in the aryl substituent. The arylpentadienyl nitriles 5 and 6 could also be converted directly into the corresponding 2-aminopyridines.
Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines
-
, (2008/06/13)
This disclosure describes novel 6-(substituted-phenyl)-1,2,4-triazolo[4,3-a]pyridines useful as hypotensive agents.
