359821-38-8

Basic information

• Product Name: 2-amino-N-(2,2,2-trifluoroethyl)acetamide
• Synonyms: 2-amino-N-(2,2,2-trifluoroethyl)acetamide
• CAS NO: 359821-38-8
• Molecular Formula: C4H7F3N2O
• Molecular Weight: 156
• Mol File: 359821-38-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 227.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.294±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 12.87±0.46(Predicted)
• CAS DataBase Reference: 2-amino-N-(2,2,2-trifluoroethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N-(2,2,2-trifluoroethyl)acetamide(359821-38-8)
• EPA Substance Registry System: 2-amino-N-(2,2,2-trifluoroethyl)acetamide(359821-38-8)

Safety Data

• Hazardous Substances Data: 359821-38-8(Hazardous Substances Data)

Usage

General Description

2-amino-N-(2,2,2-trifluoroethyl)acetamide is a chemical compound with the molecular formula C4H7F3N2O. It is a derivative of acetamide that contains a trifluoroethyl group and an amino group. 2-amino-N-(2,2,2-trifluoroethyl)acetamide is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its unique chemical properties. It is also used as a building block in organic synthesis to create more complex molecules. Additionally, it has potential applications in the development of new materials and as a reagent in chemical research.

Upstream product

• 170655-44-4 2-chloro-N-(2,2,2-trifluoroethyl)acetamide 

Downstream Products

• 1171331-39-7 1-oxo-1-N-(2,2,2-trifluoroethyl)-1,2-diaminoethane hydrochloride 
• 1093861-60-9 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide 
• 864731-61-3 A₁₄₄₃ 
• 1622864-04-3 C₂₄H₁₆Cl₂F₆N₄O₃ 
• 1416977-34-8 (E)-2-Chloro-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-4-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-1-en-1-yl)benzamide 

Relevant articles and documents

Method for preparing 2-amino-N-(2,2,2-trifluoroethyl)acetamide

The invention relates to a method for preparing 2-amino-N-(2,2,2-trifluoroethyl)acetamide and its salt. The method for preparing 2-amino-N-(2,2,2-trifluoroethyl)acetamide and its salt comprises the following steps: reacting N-phthaloyl-protected glycine with trifluoroethylamine or its salts to form amide, removing the above protective group under the action of hydrazine hydrate to obtain crude2-amino-N-(2,2,2-trifluoroethyl)acetamide, carrying out a salt formation reaction on the crude 2-amino-N-(2,2,2-trifluoroethyl)acetamide and an acid to obtain the salt of the 2-amino-N-(2,2,2-trifluoroethyl)acetamide, and adding an alkali to dissociate the 2-amino-N-(2,2,2-trifluoroethyl)acetamide. The method has the advantages of low price of a deprotection reaction reagent used in the invention, simplicity in operation, no use of flammable and explosive hydrogen, realization of the reaction temperature from room temperature to the reflux temperature of a solvent, and mild reaction conditions, and is very suitable for the production of industrial devices.