359844-93-2

Upstream product

• 359844-89-6 2-[(2H)-2-methyl-3-oxo-5-pyridazinyl]-N-pivaloylanilide 
• 153239-91-9 5-iodo-2-methylpyridazin-3(2H)-one 
• 146140-95-6 2-pivaloylaminophenyl boronic acid 
• 359844-91-0 5-(2-aminophenyl)-2-methylpyridazin-3(2H)-one 

Downstream Products

• 1346156-07-7 5-(2-triphenylphosphoranylideneaminophenyl)-2-methylpyridazin-3(2H)-one 
• 1346156-10-2 3-methyl-5-phenylamino-pyridazino[4,5-c]quinolin-4(3H)-one 
• 1346156-13-5 5-[2-(1,6-dihydro-1-methyl-6-oxopyridazin-4-yl)-phenylamino]-3-methylpyridazino[4,5-c]-quinolin-4(3H)-one 

Relevant academic research and scientific papers

Suzuki-aza-Wittig, Suzuki-condensation and aza-Wittig-electrocyclic ring-closure tandem reactions for synthesis of fused nitrogen-containing ring systems

We describe tandem combinations of Suzuki-aza-Wittig, Suzuki-condensation and aza-Wittig-electrocyclic ring closure reactions for the synthesis of new pyridazino[4,5-c]isoquinolinone, pyridazino[4,5-c]quinolinone and pyrimido[5,4-c]quinoline derivatives.

New synthetic approach to pyridazino[4,5-b]indoles by Pd(O)-catalyzed cross-coupling reaction

5-Iodo-2-methylpyridazin-3(2H)-one readily underwent Suzuki coupling with protected anilinoboronic acids to yield the corresponding arylpyridazinones which proved to be suitable starting compounds to a ring closure - a 4 step pathway - to pyridazino[4,5-b]indoles.