359866-25-4

Basic information

• Product Name: (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one
• Synonyms: (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one
• CAS NO: 359866-25-4
• Molecular Weight: 385.59
• Mol File: 359866-25-4.mol

Chemical Properties

• CAS DataBase Reference: (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one(359866-25-4)
• EPA Substance Registry System: (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one(359866-25-4)

Safety Data

• Hazardous Substances Data: 359866-25-4(Hazardous Substances Data)

Upstream product

• 359866-32-3 (3S,4S)-5-(4-hydroxybutyl)-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 359866-33-4 (4S,5S)-5-but-3-enyl-3,3-dichloro-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 359866-23-2 (4S,5S)-5-but-3-enyl-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 359866-34-5 methanesulfonic acid 4-{(2S,3R)-5-oxo-3-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-yl} butyl ester 

Downstream Products

• 359866-35-6 6,7,8,8a-tetrahydro-5H-indolizin-3-one 

Relevant articles and documents

Enantiocontrolled preparation of indolizidines: Synthesis of (-)-2-epilentiginosine and (+)-lentiginosine

A highly stereoselective approach to (-)-2-epilentiginosine and (+)-lentiginosine has been developed based on a diastereofacially selective cycloaddition of dichloroketene with a chiral dienol ether. The two naturally occurring indolizidines are each obtained enantioselectively (≥ 99:1) in ca. 8.5% overall yield.