359866-35-6

Upstream product

• 113158-92-2 (1R,8aS)-1-hydroxyhexahydroindolizin-3-one 
• 359866-34-5 methanesulfonic acid 4-{(2S,3R)-5-oxo-3-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-yl} butyl ester 
• 359866-32-3 (3S,4S)-5-(4-hydroxybutyl)-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 359866-33-4 (4S,5S)-5-but-3-enyl-3,3-dichloro-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 359866-25-4 (1R,8aS)-1-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]hexahydroindolizin-3-one 
• 359866-23-2 (4S,5S)-5-but-3-enyl-4-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]pyrrolidin-2-one 
• 393827-08-2 1-(2-vinylpiperidin-1-yl)propenoate 

Downstream Products

• 139894-04-5 hexahydro-indolizin-3-one 

Relevant academic research and scientific papers

Enantiocontrolled preparation of indolizidines: Synthesis of (-)-2-epilentiginosine and (+)-lentiginosine

A highly stereoselective approach to (-)-2-epilentiginosine and (+)-lentiginosine has been developed based on a diastereofacially selective cycloaddition of dichloroketene with a chiral dienol ether. The two naturally occurring indolizidines are each obtained enantioselectively (≥ 99:1) in ca. 8.5% overall yield.