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3-Hydroxy-1-ethylazetidin-2-one, also known as 1-ethylpiperidin-3-ol-2-one, is a chiral intermediate chemical compound belonging to the azetidinone class. It is widely recognized for its role in the synthesis of pharmaceutical compounds, particularly those with sedative and anticonvulsant properties. This versatile compound also serves as a key building block in the preparation of various heterocyclic compounds and exhibits potential biological activities, including anti-inflammatory and analgesic properties, positioning it as a promising candidate for the development of new drugs.

35995-21-2

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35995-21-2 Usage

Uses

Used in Pharmaceutical Industry:
3-Hydroxy-1-ethylazetidin-2-one is used as a chiral intermediate for the synthesis of pharmaceutical compounds, specifically those with sedative and anticonvulsant properties. Its unique structure and reactivity make it a valuable component in the development of drugs targeting various neurological conditions.
Used in Heterocyclic Compound Preparation:
In the field of organic chemistry, 3-Hydroxy-1-ethylazetidin-2-one is utilized as a key building block in the preparation of various heterocyclic compounds. Its structural versatility allows for the creation of a wide range of complex molecules with diverse applications in medicine and other industries.
Used in Anti-inflammatory and Analgesic Drug Development:
3-Hydroxy-1-ethylazetidin-2-one is studied for its potential anti-inflammatory and analgesic properties, making it a promising candidate for the development of new drugs aimed at treating pain and inflammation. Its ability to modulate biological pathways involved in these conditions positions it as a valuable asset in the search for more effective therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 35995-21-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,9 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35995-21:
(7*3)+(6*5)+(5*9)+(4*9)+(3*5)+(2*2)+(1*1)=152
152 % 10 = 2
So 35995-21-2 is a valid CAS Registry Number.

35995-21-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Hydroxy-1-ethylazetidine hydrochloride

1.2 Other means of identification

Product number -
Other names 3-amino-1-ethyl-1H-pyrazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35995-21-2 SDS

35995-21-2Downstream Products

35995-21-2Relevant academic research and scientific papers

Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents

-

, (2008/06/13)

Methods of treating cardiac arrhythmias and convulsions in warm-blooded animas and pharmaceutical compositions therefor are disclosed. The compounds useful in the methods of treatment and compositions are represented by the formula STR1 where n is 0 to 3 and R is H, C1 -C4 alkyl or arylalkyl and Ar is phenyl or substituted phenyl.

Preparation of 3-Azetidinols with Non-Bulky 1-Alkyl Substituents

Higgins, Robert H.,Eaton, Quentin L.,Worth, Leroy,Peterson, Myra V.

, p. 255 - 259 (2007/10/02)

Cyclization of either the tetrahydropyranyl or trimethylsilyl ether of 1-(alkylamino)-3-chloro-2-propanols 1 followed by cleavage of the azetidinyl ether provides a general method for the preparation of 1-alkyl-3-azetidinols.Unhindered amines provide a more facile preparation of derivatives of 1, or its ethers, than do hindered amines, while hindered derivatives of 1 undergo more facile ring closure.

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