360-80-5Relevant articles and documents
Energy barrier determination of enantiomerization of chiral 3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide type compounds by enantioselective stopped-flow HPLC
Cannazza, Giuseppe,Braghiroli, Daniela,Iuliani, Piera,Parenti, Carlo
, p. 3158 - 3162 (2006)
The synthesis and enantioseparation of chiral 3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide derivatives are reported herein. A HPLC stopped-flow procedure was applied to the determination of rate constants and free energy barriers of enantiomerization of the compounds synthesized in the presence of achiral stationary phase. The individual enantiomers of the studied compounds were isolated in parallel by preparative HPLC on a Chiraspher NT column. Rate constants and free energy barriers of enantiomerization were determined in the mobile phase. The results were used to determine the influence of the chiral stationary phase on the enantiomerization process.
Highly Enantioselective Synthesis of Cyclic Aminals with a Cyclopentadiene-Based Chiral Carboxylic Acid
Sui, Yuebo,Cui, Peng,Liu, Sensheng,Zhou, Yanmei,Du, Peng,Zhou, Haifeng
supporting information, p. 215 - 218 (2018/01/26)
A highly enantioselective aminalization of 2-aminobenzenesulfonamides and aldehydes catalyzed by a novel cyclopentadiene-based chiral carboxylic acid has been realized. The cost-effective and readily synthesized cyclopentadiene-based chiral carboxylic aci
Iron-catalyzed oxidative synthesis of N-heterocycles from primary alcohols
Zhao, Dan,Zhou, Yu-Ren,Shen, Qi,Li, Jian-Xin
, p. 6486 - 6489 (2014/02/14)
An iron-catalyzed one-pot one-step oxidative system has been successfully developed in the conversion of primary alcohols into nitrogen-containing heterocycles, such as quinazolinone, quinazoline and 3,4-dihydro-2H-1,2,4- benzothiadiazine 1,1-dioxide derivatives.
