360054-69-9

Basic information

• Product Name: 2-Imidazolidinone, 1,3-dimethyl-4,5-diphenyl-, (4R,5R)-
• CAS NO: 360054-69-9
• Molecular Formula: C17H18N2O
• Molecular Weight: 266.343
• Mol File: 360054-69-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Imidazolidinone, 1,3-dimethyl-4,5-diphenyl-, (4R,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Imidazolidinone, 1,3-dimethyl-4,5-diphenyl-, (4R,5R)-(360054-69-9)
• EPA Substance Registry System: 2-Imidazolidinone, 1,3-dimethyl-4,5-diphenyl-, (4R,5R)-(360054-69-9)

Safety Data

• Hazardous Substances Data: 360054-69-9(Hazardous Substances Data)

Upstream product

• 134731-67-2 (R,R)-trans-4,5-diphenylimidazolidin-2-one 
• 74-88-4 methyl iodide 
• 219645-17-7 (S)-N-methyl-N-(2'-formylphenyl)valine benzyl ester 

Downstream Products

• 1226668-04-7 (2S)-3-[4-(benzyloxy)phenyl]-2-{[(4R,5R)-1,3-dimethyl-4,5-diphenylimidazolidin-2-ylidene]amino}propan-1-ol 
• 1226668-06-9 4-[(2S)-2-{[(4R,5R)-1,3-dimethyl-4,5-diphenylimidazolidin-2-ylidene]amino}-3-hydroxypropyl]-phenol 
• 1398227-60-5 (4R,5R)-2-[(tert-butoxycarbonyl)methyl]imino-1,3-dimethyl-4,5-diphenylimidazolidine 
• 198625-67-1 (4R,5R)-2-Chloro-1,3-dimethyl-4,5-diphenyl-4,5-dihydro-3H-imidazol-1-ium; chloride 

Relevant articles and documents

First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines

The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing α,β-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only

Chirality transfer from guanidinium ylides to 3-alkenyl (or 3-alkynyl) aziridine-2-carboxylates and application to the syntheses of (2R,3S)-3-hydroxyleucinate and D-erythro-sphingosine

Reaction of chiral guanidinium ylides with α,β-unsaturated aldehydes gives 3-(α,β-unsaturated) aziridine-2-carboxylates in high diastereo- and enantioselectivities (up to 93% diastereomeric excess and 98% enantiomeric excess). 3-(1-Methylvinyl)- and 3-[(E)-pentadec-1-enyl]aziridine-2- carboxylates were successfully employed to prepare (2R,3S)-3-hydroxyleucinate and D-erythro-sphingosine, respectively.