360054-69-9Relevant academic research and scientific papers
First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines
Wu, Lei,Li, Guangxun,He, Migu,Wang, Yingwei,Zhao, Gang,Tang, Zhuo
supporting information, p. 769 - 772 (2016/10/24)
The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing α,β-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only
Synthesis of (-)-benzolactam-V8 by application of asymmetric aziridination
Khantikaew, Itsara,Takahashi, Masato,Kumamoto, Takuya,Suzuki, Noriyuki,Ishikawa, Tsutomu
experimental part, p. 878 - 882 (2012/01/14)
(-)-Benzolactam-V8, an artificially-designed cyclic dipeptide with strong tumor-promoter activity, was synthesized from benzyl (S)-N-(2-formylphenyl)-N- methylvalinate by application of guanidinium ylide-participated asymmetric aziridination followed by t
Chirality transfer from guanidinium ylides to 3-alkenyl (or 3-alkynyl) aziridine-2-carboxylates and application to the syntheses of (2R,3S)-3-hydroxyleucinate and D-erythro-sphingosine
Disadee, Wannaporn,Ishikawa, Tsutomu
, p. 9399 - 9406 (2007/10/03)
Reaction of chiral guanidinium ylides with α,β-unsaturated aldehydes gives 3-(α,β-unsaturated) aziridine-2-carboxylates in high diastereo- and enantioselectivities (up to 93% diastereomeric excess and 98% enantiomeric excess). 3-(1-Methylvinyl)- and 3-[(E)-pentadec-1-enyl]aziridine-2- carboxylates were successfully employed to prepare (2R,3S)-3-hydroxyleucinate and D-erythro-sphingosine, respectively.
