198625-67-1

Basic information

• Product Name: (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE
• Synonyms: (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE;Prepared Rhizome Of Rehmannia
• CAS NO: 198625-67-1
• Molecular Formula: C17H18Cl2N2
• Molecular Weight: 321.24
• Product Categories: Condensation & Active Esterification;Synthetic Organic Chemistry
• Mol File: 198625-67-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 221 °C
• Appearance: /
• CAS DataBase Reference: (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE(198625-67-1)
• EPA Substance Registry System: (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE(198625-67-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 36/37/39
• Hazardous Substances Data: 198625-67-1(Hazardous Substances Data)

Usage

General Description

The chemical (4S,5S)-2-chloro-1,3-dimethyl-4,5-diphenyl-1-imidazolinium chloride is a compound with a complex structure that includes a chloro-substituted imidazolinium ring. It is a quaternary ammonium salt and is commonly used as a catalyst in organic synthesis reactions. (4S,5S)-2-CHLORO-1,3-DIMETHYL-4,5-DIPHENYL-1-IMIDAZOLINIUM CHLORIDE has been found to exhibit potent antimicrobial and antifungal properties, and it is therefore used in various medical and agricultural applications. Additionally, it has been investigated for its potential use in the development of new drugs and pharmaceuticals. Consequently, (4S,5S)-2-chloro-1,3-dimethyl-4,5-diphenyl-1-imidazolinium chloride is a versatile compound with a range of potential applications in the fields of medicine, agriculture, and chemical synthesis.

Upstream product

• 360054-69-9 (4R,5R)-1,3-dimethyl-4,5-(diphenyl)-imidazolidin-2-one 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 22751-68-4 (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine 
• 188299-19-6 (S,S)-1,3-dimethyl-4,5-diphenylimidazolidin-2-one 

Downstream Products

• 1226668-04-7 (2S)-3-[4-(benzyloxy)phenyl]-2-{[(4R,5R)-1,3-dimethyl-4,5-diphenylimidazolidin-2-ylidene]amino}propan-1-ol 

Relevant articles and documents

Development of Chiral Organosuperbase Catalysts Consisting of Two Different Organobase Functionalities

In the field of chiral Br?nsted base catalysis, a new generation of chiral catalysts has been highly anticipated to overcome the intrinsic limitation of pronucleophiles that are applicable to the enantioselective reactions. Herein, we reveal conceptually new chiral Br?nsted base catalysts consisting of two different organobase functionalities, one of which functions as an organosuperbase and the other as the substrate recognition site. Their prominent activity, which stems from the distinctive cooperative function by the two organobases in a single catalyst molecule, was demonstrated in the unprecedented enantioselective direct Mannich-type reaction of α-phenylthioacetate as a less acidic pronucleophile. The present achievement would provide a new guiding principle for the design and development of chiral Br?nsted base catalysts and significantly broaden the utility of Br?nsted base catalysis in asymmetric organic synthesis.

Catalytic performance of polystyrene-bound ChibaG derivatives as guanidine organobases in asymmetric Michael additions

The guanidine organocatalyst, ChibaG, was bound via an ether linkage to the phenyl group of the 2-imino substituent to Merrifield resin. Polystyrene-bound ChibaG acted as an effective catalyst in the Michael reaction of tert-butyl N-(diphenylmethylidene)g

Pentanidium-catalyzed enantioselective α-hydroxylation of oxindoles using molecular oxygen

Pentanidium-catalyzed α-hydroxylation of 3-substituted-2-oxindoles using molecular oxygen has been developed with good yields and enantioselectivities. This reaction does not require an additional reductant such as triethyl phosphite, which was typically added to reduce the peroxide intermediate. The reaction was demonstrated to consist of two-steps: an enantioselective formation of hydroperoxide oxindole and a kinetic resolution of the hydroperoxide oxindole via reduction with enolates generated from the oxindoles.