3603-15-4

Basic information

• Product Name: 4(1H)-Pyrimidinone, 5-ethyl-6-hydroxy- (9CI)
• Synonyms: 4(1H)-Pyrimidinone, 5-ethyl-6-hydroxy- (9CI);5-ethyl-6-hydroxypyrimidin-4(3H)-one
• CAS NO: 3603-15-4
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.13992
• Product Categories: PYRIMIDINE
• Mol File: 3603-15-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4(1H)-Pyrimidinone, 5-ethyl-6-hydroxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 5-ethyl-6-hydroxy- (9CI)(3603-15-4)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 5-ethyl-6-hydroxy- (9CI)(3603-15-4)

Safety Data

• Hazardous Substances Data: 3603-15-4(Hazardous Substances Data)

Upstream product

• 6082-49-1 ethyl propanediamide 
• 77287-34-4 formamide 
• 26717-67-9 dimethyl ethylmalonate 
• 3473-63-0 formamidine acetic acid 
• 133-13-1 ethyl diethyl malonate 

Downstream Products

• 1428249-60-8 5-ethyl-6-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(2-(3-fluoroazetidin-1-yl)ethyl)-1H-imidazol-2-yl)piperidin-1-yl)pyrimidin-4-amine 
• 53967-81-0 4,6-dichloro-5-ethylpyrimidine 
• 125415-05-6 4-(6-Ethyl-5-oxo-5H-[1,2,4]triazin-2-yl)-benzoic acid 
• 125415-03-4 2-(4-Bromo-phenyl)-6-ethyl-2H-[1,2,4]triazin-5-one 
• 125415-04-5 6-ethyl-2-p-chlorophenyl-1,2,4-triazin-5(2H)-one 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS

Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound of formula (XXXII), and methods of using a compound of formula (XXXII), e.g., in the treatment or prevention of skin disorders.

Synthesis of new 5-substituted pyrimidine acyclonucleosides

Acyclonucleosides of pyrimidine were prepared by condensing appropriately silylated 5-substituted pyrimidines with an acyclic side chain in the form of an acetylated haloalkoxyalcohol and subsequent removal of the protecting acetyl group in base. Also, ac