6082-49-1

Basic information

• Product Name: Ethylmalonamide
• Synonyms: Ethylmalonamide;Propane-1,1-dicarboxamide
• CAS NO: 6082-49-1
• Molecular Formula: C₅H₁₀N₂O₂
• Molecular Weight: 130.1451
• Mol File: 6082-49-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 389.2°Cat760mmHg
• Flash Point: 189.2°C
• Appearance: /
• Density: 1.151g/cm³
• Vapor Pressure: 2.9E-06mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: Ethylmalonamide(CAS DataBase Reference)
• NIST Chemistry Reference: Ethylmalonamide(6082-49-1)
• EPA Substance Registry System: Ethylmalonamide(6082-49-1)

Safety Data

• Hazardous Substances Data: 6082-49-1(Hazardous Substances Data)

Usage

General Description

Ethylmalonamide is a compound that belongs to the class of amides and is derived from malonic acid. It is a colorless solid that is soluble in water and organic solvents. Ethylmalonamide is often used as a reactive intermediate in various chemical processes, including the synthesis of pharmaceuticals and agrochemicals. It can also act as a chelating agent, binding to metal ions in solution. Ethylmalonamide has low toxicity and is generally considered safe for use in industrial and laboratory settings. However, like all chemicals, it should be handled with caution and according to proper safety protocols.

InChI:InChI=1/C5H10N2O2/c1-2-3(4(6)8)5(7)9/h3H,2H2,1H3,(H2,6,8)(H2,7,9)

Upstream product

• 133-13-1 ethyl diethyl malonate 
• 26717-67-9 dimethyl ethylmalonate 
• 601-75-2 ethylmalonic acid 
• 5813-85-4 cyclopropane-1,1-dicarboxylic acid amide [4-(3-fluoro-benzyloxy)-phenyl]-amide 
• 108-13-4 malonodiamide 
• 75-03-6 ethyl iodide 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 
• 98024-97-6 ethyl-malonyl bromide 

Downstream Products

• 10256-07-2 2-ethyl-N,N'-diphenylmalondiamide 
• 15601-59-9 ethyl-malonic acid amid-anilide 
• 2518-72-1 5-ethyl barbituric acid 
• 53967-81-0 4,6-dichloro-5-ethylpyrimidine 
• 3603-15-4 5-ethylpyrimidine-4,6-diol 
• 15601-90-8 2-ethyl-N-phenyl-malonamic acid 
• 57-43-2 amobarbital 
• 3603-15-4 5-ethyl-4-hydroxypyrimidin-6(1H)-one 
• 146764-92-3 3-ethyl-1-methyl-1H-quinoline-2,4-dione 
• 29141-71-7 2,2-Diethyl-malonamide 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS

Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound of formula (XXXII), and methods of using a compound of formula (XXXII), e.g., in the treatment or prevention of skin disorders.

Translocative Rearrangements. Generality of the Formamidine-Induced Rearrangement of 4-Substituted 5-Amino-4-cyano-4H-imidazoles

The generality of two different courses of cyclisation reactions for 4-substituted 5-amino-4-cyano-4H-imidazoles (5) is demonstrated.One results from treatment of 5 with formamidine in a "translocative rearrangement" that leads to 8-substituted 4-aminoimi

Hydrogenolysis of Small Cycloalkanes, VII. Selective Hydrogenation of 1,1-Disubstituted Cyclopropane Derivatives

On hydrogenation of 1,1-disubstituted cyclopropane derivatives 1 hydrogenolysis of the C-2-C-3 bond to yield 2 is promoted by electron releasing groups (R =alkyl, CH2OH, OR).On the other hand the presence of electron attracting substituents (R = CO2R, COR, CN) causes opening of the C-1-C-2 bond and formation of products 3. 1,1-Bis(trifluoromethyl)cyclopropane could not be hydrogenated.