36034-54-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Methoxyisoquinoline is used as a potential drug candidate for its ability to inhibit the growth of certain cancer cells, making it a valuable asset in the development of new anticancer therapies.
Used in Analytical Chemistry:
4-Methoxyisoquinoline is used as a fluorescent probe due to its optical properties, which allow for its application in various analytical techniques and detection methods.
Used in Bioimaging Applications:
4-Methoxyisoquinoline is utilized as a fluorescent marker in bioimaging, enabling the visualization and tracking of biological processes at the molecular level, which is crucial for understanding disease mechanisms and developing targeted therapies.

Upstream product

• 76570-11-1 4--methoxyisoquinoline N--oxide 
• 67-56-1 methanol 
• 1532-97-4 4-bromoisoquinoline 
• 865-33-8 potassium methanolate 

Relevant academic research and scientific papers

Oxidative Addition Complexes as Precatalysts for Cross-Coupling Reactions Requiring Extremely Bulky Biarylphosphine Ligands

In this report, we describe the application of palladium-based oxidative addition complexes (OACs) as effective precatalysts for C-N, C-O, and C-F cross-coupling reactions with a variety of (hetero)arenes. These complexes offer a convenient alternative to previously developed classes of precatalysts, particularly in the case of the bulkiest biarylphosphine ligands, for which palladacycle-based precatalysts do not readily form. The precatalysts described herein are easily prepared and stable to long-term storage under air.

Mild and general palladium-catalyzed synthesis of methyl aryl ethers enabled by the use of a palladacycle precatalyst

A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.

Photochemistry of Methoxy-substituted Quinoline and Isoquinoline N-Oxides

The photochemistry of quinoline 1-oxides and isoquinoline 2-oxides bearing a methoxy-group in the pyridine ring was investigated in protic and aprotic media.The formation of various photoisomers, viz. 3,1-benzoxazepines, 2(1H)-quinolones, N-(2-isocyanobenzyl)formamides, 4(1H)-quinolones, and 3-hydroxyquinolines from the different methoxyquinoline 1-oxides, and 1,3-benzoxazepines and 1(2H)-isoquinolones from the different methoxyisoquinoline 2-oxides, was observed along with deoxygenation and formation of products derived from hydration and decomposition of the primary products.The position of the methoxy-group has an important directing effect on the photoreactions.