36050-92-7Relevant academic research and scientific papers
A simple resolution procedure using the Staudinger reaction for the preparation of P-stereogenic phosphine oxides
Andersen,Ramsden,Che,Parvez,Keay
, p. 7478 - 7486 (2007/10/03)
The resolution of a variety of (±)-P-stereogenic phosphines is achieved by exploiting the Staudinger reaction of a (±)-phosphine with enantiopure (1S,2R)-O-(tert-butyldimethylsilyl)isobornyl-10-sulfonyl azide. The resulting mixtures of diastereomeric phosphinimines are generally separable by fractional crystallization or flash chromatography. Subsequent acid-catalyzed hydrolysis provides the corresponding optically pure phosphine oxides in high yields.
A novel synthesis of unsymmetrical tertiary phosphines: Selective nucleophilic substitution on phosphorus(III)
Singh, Sumita,Nicholas, Kenneth M.
, p. 149 - 150 (2007/10/03)
A new synthesis of unsymmetrical tertiary phosphines has been developed employing selective, sequential alkylation of chloroaminophospnines by Grignard and organolithium reagents.
Preparation of Alkylmethylphenylphosphines by the Method of Hewertson and Watson
Wolfsberger, Werner
, p. 295 - 298 (2007/10/02)
The reaction of C6H5(CH3)PNa with some alkyl halides in liquid ammonia was studied.The resulting phosphines were characterized by elemental analyses, NMR spectra, and by the reaction with trimethylsilyl azide giving trimethylsilylimino triorganophosphoranes. - Keywords: Alkylmethylphenylphosphines, N-Trimethylsilylimino Triorganophosphoranes, NMR Spectra
