360553-94-2Relevant academic research and scientific papers
Structure-activity relationships of non-imidazole H3 receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists
Gfesser, Gregory A.,Zhang, Henry,Dinges, Jurgen,Fox, Gerard B.,Pan, Jia Bao,Esbenshade, Timothy A.,Yao, Betty B.,Witte, David,Miller, Thomas R.,Kang, Chae-Hee,Krueger, Kathy M.,Bennani, Youssef L.,Hancock, Arthur A.,Faghih, Ramin
, p. 673 - 676 (2007/10/03)
Further SAR studies on novel histamine H3 receptor antagonists are presented. Compound 14bb is a potent antagonist of both the rat cortical and human clone receptors, and is demonstrated to act functionally as an antagonist in an in vivo mouse dipsogenia model.
Cyclic and bicyclic diamino histamine-3 receptor antagonists
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, (2008/06/13)
Compounds of formula (I) compounds of formula (II) compounds of formula (III) and compounds of formula (IV) or pharmaceutically acceptable salts thereof are useful as H3 receptor antagonists. Processes to make the compounds and methods of treat
