873547-02-5Relevant academic research and scientific papers
Structure-activity relationships of non-imidazole H3 receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists
Gfesser, Gregory A.,Zhang, Henry,Dinges, Jurgen,Fox, Gerard B.,Pan, Jia Bao,Esbenshade, Timothy A.,Yao, Betty B.,Witte, David,Miller, Thomas R.,Kang, Chae-Hee,Krueger, Kathy M.,Bennani, Youssef L.,Hancock, Arthur A.,Faghih, Ramin
, p. 673 - 676 (2004)
Further SAR studies on novel histamine H3 receptor antagonists are presented. Compound 14bb is a potent antagonist of both the rat cortical and human clone receptors, and is demonstrated to act functionally as an antagonist in an in vivo mouse dipsogenia model.
